Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | LRRC61 | leucine rich repeat containing 61 (259 aa) | ||||||||||||
Predicted Functional Partners:
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 | KRBA1 | KRAB-A domain containing 1 (1029 aa) |
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0.649 | ||||||||||
 | PPP1R11 | protein phosphatase 1, regulatory (inhibitor) subunit 11 (126 aa) |
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0.553 | |||||||||
 | POTEE | POTE ankyrin domain family member E (1075 aa) |
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0.526 | |||||||||
 | POTEI | POTE ankyrin domain family, member I (1075 aa) |
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0.526 | |||||||||
 | POTEJ | POTE ankyrin domain family, member J (1038 aa) |
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0.526 | |||||||||
 | POTEF | POTE ankyrin domain family, member F (1075 aa) |
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0.526 | |||||||||
 | ZNF783 | zinc finger family member 783; May be involved in transcriptional regulation (546 aa) |
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0.517 | |||||||||
 | C7orf29 | chromosome 7 open reading frame 29 (236 aa) |
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0.472 | ||||||||||
 | PNPLA6 | patatin-like phospholipase domain containing 6; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (1375 aa) |
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0.452 | |||||||||
 | PNPLA7 | patatin-like phospholipase domain containing 7 (1342 aa) |
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0.452 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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