node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C19orf47 | LRFN1 | ENSP00000463159 | ENSP00000248668 | chromosome 19 open reading frame 47 | leucine rich repeat and fibronectin type III domain containing 1; Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity) | 0.509 |
C19orf47 | SAMD4B | ENSP00000463159 | ENSP00000317224 | chromosome 19 open reading frame 47 | sterile alpha motif domain containing 4B; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A | 0.583 |
C19orf47 | TTC9B | ENSP00000463159 | ENSP00000311760 | chromosome 19 open reading frame 47 | tetratricopeptide repeat domain 9B | 0.757 |
C19orf47 | ZNF546 | ENSP00000463159 | ENSP00000339823 | chromosome 19 open reading frame 47 | zinc finger protein 546; May be involved in transcriptional regulation | 0.722 |
ECD | ZNF546 | ENSP00000401566 | ENSP00000339823 | ecdysoneless homolog (Drosophila); Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes | zinc finger protein 546; May be involved in transcriptional regulation | 0.577 |
KDM2A | ZNF546 | ENSP00000432786 | ENSP00000339823 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 546; May be involved in transcriptional regulation | 0.501 |
LRFN1 | C19orf47 | ENSP00000248668 | ENSP00000463159 | leucine rich repeat and fibronectin type III domain containing 1; Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity) | chromosome 19 open reading frame 47 | 0.509 |
LRFN1 | TTC9B | ENSP00000248668 | ENSP00000311760 | leucine rich repeat and fibronectin type III domain containing 1; Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity) | tetratricopeptide repeat domain 9B | 0.509 |
LRFN1 | ZNF546 | ENSP00000248668 | ENSP00000339823 | leucine rich repeat and fibronectin type III domain containing 1; Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity) | zinc finger protein 546; May be involved in transcriptional regulation | 0.526 |
LRRC66 | TAF1L | ENSP00000341944 | ENSP00000418379 | leucine rich repeat containing 66 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | 0.556 |
LRRC66 | ZFAND4 | ENSP00000341944 | ENSP00000339484 | leucine rich repeat containing 66 | zinc finger, AN1-type domain 4 | 0.636 |
LRRC66 | ZNF546 | ENSP00000341944 | ENSP00000339823 | leucine rich repeat containing 66 | zinc finger protein 546; May be involved in transcriptional regulation | 0.673 |
SAMD4B | C19orf47 | ENSP00000317224 | ENSP00000463159 | sterile alpha motif domain containing 4B; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A | chromosome 19 open reading frame 47 | 0.583 |
SAMD4B | TTC9B | ENSP00000317224 | ENSP00000311760 | sterile alpha motif domain containing 4B; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A | tetratricopeptide repeat domain 9B | 0.583 |
SAMD4B | ZNF546 | ENSP00000317224 | ENSP00000339823 | sterile alpha motif domain containing 4B; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A | zinc finger protein 546; May be involved in transcriptional regulation | 0.539 |
TAF1L | LRRC66 | ENSP00000418379 | ENSP00000341944 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | leucine rich repeat containing 66 | 0.556 |
TAF1L | ZFAND4 | ENSP00000418379 | ENSP00000339484 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | zinc finger, AN1-type domain 4 | 0.554 |
TAF1L | ZNF546 | ENSP00000418379 | ENSP00000339823 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like; May act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced | zinc finger protein 546; May be involved in transcriptional regulation | 0.633 |
TTC9B | C19orf47 | ENSP00000311760 | ENSP00000463159 | tetratricopeptide repeat domain 9B | chromosome 19 open reading frame 47 | 0.757 |
TTC9B | LRFN1 | ENSP00000311760 | ENSP00000248668 | tetratricopeptide repeat domain 9B | leucine rich repeat and fibronectin type III domain containing 1; Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity) | 0.509 |