node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDOB | ENO1 | ENSP00000363988 | ENSP00000234590 | aldolase B, fructose-bisphosphate | enolase 1, (alpha) | 0.906 |
ALDOB | ENO2 | ENSP00000363988 | ENSP00000229277 | aldolase B, fructose-bisphosphate | enolase 2 (gamma, neuronal); Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity) | 0.856 |
ALDOB | ENO3 | ENSP00000363988 | ENSP00000324105 | aldolase B, fructose-bisphosphate | enolase 3 (beta, muscle); Appears to have a function in striated muscle development and regeneration | 0.981 |
ALDOB | GPI | ENSP00000363988 | ENSP00000405573 | aldolase B, fructose-bisphosphate | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.980 |
ALDOB | PFKL | ENSP00000363988 | ENSP00000269848 | aldolase B, fructose-bisphosphate | phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.988 |
ALDOB | PFKM | ENSP00000363988 | ENSP00000345771 | aldolase B, fructose-bisphosphate | phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.988 |
ALDOB | PFKP | ENSP00000363988 | ENSP00000370517 | aldolase B, fructose-bisphosphate | phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.988 |
ALDOB | PGK1 | ENSP00000363988 | ENSP00000362413 | aldolase B, fructose-bisphosphate | phosphoglycerate kinase 1; In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) | 0.822 |
ALDOB | PGK2 | ENSP00000363988 | ENSP00000305995 | aldolase B, fructose-bisphosphate | phosphoglycerate kinase 2 | 0.845 |
ALDOB | PKLR | ENSP00000363988 | ENSP00000339933 | aldolase B, fructose-bisphosphate | pyruvate kinase, liver and RBC; Plays a key role in glycolysis (By similarity) | 0.939 |
ENO1 | ALDOB | ENSP00000234590 | ENSP00000363988 | enolase 1, (alpha) | aldolase B, fructose-bisphosphate | 0.906 |
ENO1 | ENO3 | ENSP00000234590 | ENSP00000324105 | enolase 1, (alpha) | enolase 3 (beta, muscle); Appears to have a function in striated muscle development and regeneration | 0.766 |
ENO1 | GPI | ENSP00000234590 | ENSP00000405573 | enolase 1, (alpha) | glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons | 0.937 |
ENO1 | PFKL | ENSP00000234590 | ENSP00000269848 | enolase 1, (alpha) | phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.942 |
ENO1 | PFKM | ENSP00000234590 | ENSP00000345771 | enolase 1, (alpha) | phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.941 |
ENO1 | PFKP | ENSP00000234590 | ENSP00000370517 | enolase 1, (alpha) | phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP | 0.942 |
ENO1 | PGK1 | ENSP00000234590 | ENSP00000362413 | enolase 1, (alpha) | phosphoglycerate kinase 1; In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein) | 0.992 |
ENO1 | PGK2 | ENSP00000234590 | ENSP00000305995 | enolase 1, (alpha) | phosphoglycerate kinase 2 | 0.986 |
ENO1 | PKLR | ENSP00000234590 | ENSP00000339933 | enolase 1, (alpha) | pyruvate kinase, liver and RBC; Plays a key role in glycolysis (By similarity) | 0.995 |
ENO2 | ALDOB | ENSP00000229277 | ENSP00000363988 | enolase 2 (gamma, neuronal); Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity) | aldolase B, fructose-bisphosphate | 0.856 |