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STRINGSTRING
AGBL2 AGBL2 PGA4 PGA4 SLC24A6 SLC24A6 KRCC1 KRCC1 MPLKIP MPLKIP PGA5 PGA5 PGA3 PGA3
"KRCC1" - lysine-rich coiled-coil 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
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Experiments
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Textmining
[Homology]
Score
KRCC1lysine-rich coiled-coil 1 (259 aa)    
Predicted Functional Partners:
SLC24A6
solute carrier family 24 (sodium/lithium/calcium exchanger), member 6; Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis. Regulates rates of glucose-dependent insulin secretion in pancreatic beta- cells during the first phase of insulin secretion- acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. I [...] (584 aa)
            score_image   0.540
MPLKIP
M-phase specific PLK1 interacting protein; May play a role in maintenance of cell cycle integrity by regulating mitosis or cytokinesis (179 aa)
            score_image   0.503
PGA5
pepsinogen 5, group I (pepsinogen A); Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent (388 aa)
            score_image   0.473
PGA4
pepsinogen 4, group I (pepsinogen A); Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent (388 aa)
            score_image   0.471
AGBL2
ATP/GTP binding protein-like 2; Metallocarboxypeptidase that may play a role in the processing of tubulin (By similarity) (902 aa)
            score_image   0.470
PGA3
pepsinogen 3, group I (pepsinogen A); Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent (388 aa)
            score_image   0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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