THEG protein (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Score

THEG

theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity) (379 aa)

Predicted Functional Partners:

CCT5

0.991

RHBDF2

0.475

BFSP2

0.470

ING2

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BFSP2	THEG	ENSP00000304987	ENSP00000340088	beaded filament structural protein 2, phakinin; Involved in stabilization of lens fiber cell cytoskeleton (By similarity)	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	0.470
CCT5	THEG	ENSP00000280326	ENSP00000340088	chaperonin containing TCP1, subunit 5 (epsilon); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	0.991
ING2	THEG	ENSP00000307183	ENSP00000340088	inhibitor of growth family, member 2; Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs)	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	0.414
RHBDF2	THEG	ENSP00000322775	ENSP00000340088	rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	0.475
THEG	BFSP2	ENSP00000340088	ENSP00000304987	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	beaded filament structural protein 2, phakinin; Involved in stabilization of lens fiber cell cytoskeleton (By similarity)	0.470
THEG	CCT5	ENSP00000340088	ENSP00000280326	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	chaperonin containing TCP1, subunit 5 (epsilon); Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin	0.991
THEG	ING2	ENSP00000340088	ENSP00000307183	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	inhibitor of growth family, member 2; Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs)	0.414
THEG	RHBDF2	ENSP00000340088	ENSP00000322775	theg spermatid protein; May be involved (but not essential) in spermatogenesis (By similarity)	rhomboid 5 homolog 2 (Drosophila); Rhomboid protease-like protein which has no protease activity but regulates the secretion of several ligands of the epidermal growth factor receptor. Indirectly activates the epidermal growth factor receptor signaling pathway and may thereby regulate sleep, cell survival, proliferation and migration (By similarity)	0.475

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