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CD2 CD2 CD46 CD46 CD55 CD55 CD59 CD59 C8A C8A C8B C8B C9 C9 C8G C8G C5 C5 C6 C6 C7 C7
CD59 molecule, complement regulatory protein in Homo sapiens
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Predicted Interactions
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CD59CD59 molecule, complement regulatory protein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase (128 aa)    
Predicted Functional Partners:
C9
complement component 9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC (559 aa)
        score_image score_image score_image   0.986
C8A
complement component 8, alpha polypeptide; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself (584 aa)
        score_image score_image score_image   0.955
CD2
CD2 molecule; CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function (351 aa)
        score_image   score_image   0.943
C8B
complement component 8, beta polypeptide; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (591 aa)
          score_image score_image   0.927
C5
complement component 5; Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled (1676 aa)
          score_image score_image   0.907
C6
complement component 6; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (934 aa)
          score_image score_image   0.902
C8G
complement component 8, gamma polypeptide; C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol (202 aa)
          score_image score_image   0.901
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group); This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (440 aa)
            score_image   0.901
C7
complement component 7; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor (843 aa)
          score_image     0.900
CD46
CD46 molecule, complement regulatory protein (399 aa)
            score_image   0.814
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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