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STRINGSTRING
RAB3IP RAB3IP ZFYVE26 ZFYVE26 MLLT4 MLLT4 ACTN1 ACTN1 SSX2IP SSX2IP VAV2 VAV2 ACTN2 ACTN2 UBC UBC ACTN4 ACTN4 USP11 USP11 ARNT2 ARNT2
"SSX2IP" - synovial sarcoma, X breakpoint 2 interacting protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSX2IPsynovial sarcoma, X breakpoint 2 interacting protein (614 aa)    
Predicted Functional Partners:
MLLT4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 (1651 aa)
        score_image score_image score_image   0.981
ACTN1
actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (914 aa)
        score_image score_image score_image   0.914
ACTN2
actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (894 aa)
        score_image score_image     0.911
VAV2
vav 2 guanine nucleotide exchange factor (878 aa)
            score_image   0.812
ACTN4
actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (911 aa)
          score_image score_image   0.805
USP11
ubiquitin specific peptidase 11; Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks (963 aa)
        score_image   score_image   0.767
RAB3IP
RAB3A interacting protein (rabin3) (476 aa)
            score_image   0.767
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2; Specifically recognizes the xenobiotic response element (XRE) (717 aa)
        score_image       0.691
ZFYVE26
zinc finger, FYVE domain containing 26 (2539 aa)
        score_image       0.633
UBC
ubiquitin C (685 aa)
        score_image       0.620
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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