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STRINGSTRING
SCARB1 SCARB1 GMFG GMFG CTSG CTSG MAP3K9 MAP3K9 GMFB GMFB AP4B1 AP4B1 ZDHHC1 ZDHHC1 UAP1L1 UAP1L1 B3GALT4 B3GALT4 RPRML RPRML MAP3K11 MAP3K11
"ZDHHC1" - zinc finger, DHHC-type containing 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZDHHC1zinc finger, DHHC-type containing 1 (485 aa)    
Predicted Functional Partners:
GMFB
glia maturation factor, beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells (142 aa)
            score_image   0.649
AP4B1
adaptor-related protein complex 4, beta 1 subunit; Subunit of novel type of clathrin- or non-clathrin- associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (739 aa)
            score_image   0.633
CTSG
cathepsin G; Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride (255 aa)
            score_image   0.609
B3GALT4
UDP-Gal-betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 (378 aa)
            score_image   0.571
GMFG
glia maturation factor, gamma (142 aa)
            score_image   0.530
MAP3K9
mitogen-activated protein kinase kinase kinase 9; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial [...] (1118 aa)
        score_image   score_image   0.517
RPRML
reprimo-like (120 aa)
            score_image   0.502
MAP3K11
mitogen-activated protein kinase kinase kinase 11; Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle (847 aa)
        score_image   score_image   0.485
SCARB1
scavenger receptor class B, member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for h [...] (509 aa)
            score_image   0.475
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 (507 aa)
            score_image   0.459
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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