| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH16A1 | PIH1D1 | ENSP00000293350 | ENSP00000262265 | aldehyde dehydrogenase 16 family, member A1 | PIH1 domain containing 1 | 0.719 |
| ALDH16A1 | PPFIA3 | ENSP00000293350 | ENSP00000335614 | aldehyde dehydrogenase 16 family, member A1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates | 0.521 |
| ALDH16A1 | SYT3 | ENSP00000293350 | ENSP00000340914 | aldehyde dehydrogenase 16 family, member A1 | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.554 |
| AP2A1 | SYT3 | ENSP00000351926 | ENSP00000340914 | adaptor-related protein complex 2, alpha 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as [...] | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.567 |
| KCNC1 | SYT3 | ENSP00000265969 | ENSP00000340914 | potassium voltage-gated channel, Shaw-related subfamily, member 1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.455 |
| KLK4 | SYT3 | ENSP00000326159 | ENSP00000340914 | kallikrein-related peptidase 4; Involved in enamel formation | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.606 |
| NPS | SYT3 | ENSP00000381105 | ENSP00000340914 | neuropeptide S; Modulates arousal and anxiety. May play an important anorexigenic role. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations (By similarity) | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.497 |
| PIH1D1 | ALDH16A1 | ENSP00000262265 | ENSP00000293350 | PIH1 domain containing 1 | aldehyde dehydrogenase 16 family, member A1 | 0.719 |
| PIH1D1 | PPFIA3 | ENSP00000262265 | ENSP00000335614 | PIH1 domain containing 1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates | 0.496 |
| PIH1D1 | SYT3 | ENSP00000262265 | ENSP00000340914 | PIH1 domain containing 1 | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.597 |
| PPFIA3 | ALDH16A1 | ENSP00000335614 | ENSP00000293350 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates | aldehyde dehydrogenase 16 family, member A1 | 0.521 |
| PPFIA3 | PIH1D1 | ENSP00000335614 | ENSP00000262265 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates | PIH1 domain containing 1 | 0.496 |
| PPFIA3 | SYT3 | ENSP00000335614 | ENSP00000340914 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3; May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.436 |
| SNAP25 | SYT3 | ENSP00000254976 | ENSP00000340914 | synaptosomal-associated protein, 25kDa | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.576 |
| SNAP25 | SYT5 | ENSP00000254976 | ENSP00000346265 | synaptosomal-associated protein, 25kDa | synaptotagmin V; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)- dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity) | 0.905 |
| SYNCRIP | SYT3 | ENSP00000358635 | ENSP00000340914 | synaptotagmin binding, cytoplasmic RNA interacting protein | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | 0.585 |
| SYT3 | ALDH16A1 | ENSP00000340914 | ENSP00000293350 | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | aldehyde dehydrogenase 16 family, member A1 | 0.554 |
| SYT3 | AP2A1 | ENSP00000340914 | ENSP00000351926 | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | adaptor-related protein complex 2, alpha 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as [...] | 0.567 |
| SYT3 | KCNC1 | ENSP00000340914 | ENSP00000265969 | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | potassium voltage-gated channel, Shaw-related subfamily, member 1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient | 0.455 |
| SYT3 | KLK4 | ENSP00000340914 | ENSP00000326159 | synaptotagmin III; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity) | kallikrein-related peptidase 4; Involved in enamel formation | 0.606 |
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