KLHL6 protein (Homo sapiens) - STRING network view

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KLHL6

kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity) (621 aa)

Predicted Functional Partners:

UBC

0.634

PPP1R1B

0.612

KLHL7

0.567

LZTR1

0.528

KBTBD13

0.467

PDCD10

0.447

KLHDC10

0.414

GTDC2

0.400

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GTDC2	KLHDC10	ENSP00000344125	ENSP00000334140	glycosyltransferase-like domain containing 2	kelch domain containing 10	0.490
GTDC2	KLHL6	ENSP00000344125	ENSP00000341342	glycosyltransferase-like domain containing 2	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	0.400
KBTBD13	KLHDC10	ENSP00000388723	ENSP00000334140	kelch repeat and BTB (POZ) domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex	kelch domain containing 10	0.669
KBTBD13	KLHL6	ENSP00000388723	ENSP00000341342	kelch repeat and BTB (POZ) domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	0.467
KBTBD13	UBC	ENSP00000388723	ENSP00000344818	kelch repeat and BTB (POZ) domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex	ubiquitin C	0.576
KLHDC10	GTDC2	ENSP00000334140	ENSP00000344125	kelch domain containing 10	glycosyltransferase-like domain containing 2	0.490
KLHDC10	KBTBD13	ENSP00000334140	ENSP00000388723	kelch domain containing 10	kelch repeat and BTB (POZ) domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex	0.669
KLHDC10	KLHL6	ENSP00000334140	ENSP00000341342	kelch domain containing 10	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	0.414
KLHDC10	UBC	ENSP00000334140	ENSP00000344818	kelch domain containing 10	ubiquitin C	0.417
KLHL6	GTDC2	ENSP00000341342	ENSP00000344125	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	glycosyltransferase-like domain containing 2	0.400
KLHL6	KBTBD13	ENSP00000341342	ENSP00000388723	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	kelch repeat and BTB (POZ) domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex	0.467
KLHL6	KLHDC10	ENSP00000341342	ENSP00000334140	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	kelch domain containing 10	0.414
KLHL6	KLHL7	ENSP00000341342	ENSP00000343273	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	kelch-like 7 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates ’Lys-48’-linked ubiquitination	0.567
KLHL6	LZTR1	ENSP00000341342	ENSP00000215739	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis	0.528
KLHL6	PDCD10	ENSP00000341342	ENSP00000376506	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	programmed cell death 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and MST4 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity)	0.447
KLHL6	PPP1R1B	ENSP00000341342	ENSP00000254079	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	protein phosphatase 1, regulatory (inhibitor) subunit 1B; Inhibitor of protein-phosphatase 1	0.612
KLHL6	UBC	ENSP00000341342	ENSP00000344818	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	ubiquitin C	0.634
KLHL7	KLHL6	ENSP00000343273	ENSP00000341342	kelch-like 7 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates ’Lys-48’-linked ubiquitination	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	0.567
KLHL7	UBC	ENSP00000343273	ENSP00000344818	kelch-like 7 (Drosophila); Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates ’Lys-48’-linked ubiquitination	ubiquitin C	0.910
LZTR1	KLHL6	ENSP00000215739	ENSP00000341342	leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis	kelch-like 6 (Drosophila); Involved in B-lymphocyte antigen receptor signaling and germinal center formation (By similarity)	0.528

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