B4GALNT1 protein (Homo sapiens) - STRING network view

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B4GALNT1

beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2 (533 aa)

Predicted Functional Partners:

ST8SIA1

0.977

ST3GAL5

0.959

ST8SIA5

0.927

GLB1

0.903

SLC33A1

0.900

GBGT1

0.870

GALNT8

0.860

B4GALT6

0.852

GALNT4

0.813

GALNT1

0.811

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4GALNT1	B4GALT6	ENSP00000341562	ENSP00000306459	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; Required for the biosynthesis of glycosphingolipids	0.852
B4GALNT1	GALNT1	ENSP00000341562	ENSP00000269195	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7	0.811
B4GALNT1	GALNT4	ENSP00000341562	ENSP00000436604	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates ’Thr-57’ of SELPLG	0.813
B4GALNT1	GALNT8	ENSP00000341562	ENSP00000252318	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8); Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor (By similarity)	0.860
B4GALNT1	GBGT1	ENSP00000341562	ENSP00000361110	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens	0.870
B4GALNT1	GLB1	ENSP00000341562	ENSP00000306920	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	galactosidase, beta 1; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans	0.903
B4GALNT1	SLC33A1	ENSP00000341562	ENSP00000352456	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	solute carrier family 33 (acetyl-CoA transporter), member 1; Probable acetyl-CoA transporter necessary for O- acetylation of gangliosides	0.900
B4GALNT1	ST3GAL5	ENSP00000341562	ENSP00000366549	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide)	0.959
B4GALNT1	ST8SIA1	ENSP00000341562	ENSP00000379353	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid	0.977
B4GALNT1	ST8SIA5	ENSP00000341562	ENSP00000321343	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively	0.927
B4GALT6	B4GALNT1	ENSP00000306459	ENSP00000341562	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; Required for the biosynthesis of glycosphingolipids	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	0.852
B4GALT6	GLB1	ENSP00000306459	ENSP00000306920	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; Required for the biosynthesis of glycosphingolipids	galactosidase, beta 1; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans	0.806
B4GALT6	ST3GAL5	ENSP00000306459	ENSP00000366549	UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; Required for the biosynthesis of glycosphingolipids	ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide)	0.837
GALNT1	B4GALNT1	ENSP00000269195	ENSP00000341562	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	0.811
GALNT1	GALNT4	ENSP00000269195	ENSP00000436604	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates ’Thr-57’ of SELPLG	0.904
GALNT1	GALNT8	ENSP00000269195	ENSP00000252318	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8); Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor (By similarity)	0.903
GALNT1	GBGT1	ENSP00000269195	ENSP00000361110	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7	globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens	0.472
GALNT4	B4GALNT1	ENSP00000436604	ENSP00000341562	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates ’Thr-57’ of SELPLG	beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2	0.813
GALNT4	GALNT1	ENSP00000436604	ENSP00000269195	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates ’Thr-57’ of SELPLG	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7	0.904
GALNT4	GALNT8	ENSP00000436604	ENSP00000252318	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates ’Thr-57’ of SELPLG	UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8); Probably catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor (By similarity)	0.905

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