node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL11A1 | COL16A1 | ENSP00000359114 | ENSP00000362776 | collagen, type XI, alpha 1 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | 0.925 |
COL11A1 | COL2A1 | ENSP00000359114 | ENSP00000369889 | collagen, type XI, alpha 1 | collagen, type II, alpha 1 | 0.928 |
COL11A1 | COL3A1 | ENSP00000359114 | ENSP00000304408 | collagen, type XI, alpha 1 | collagen, type III, alpha 1 | 0.920 |
COL11A1 | COL5A1 | ENSP00000359114 | ENSP00000360882 | collagen, type XI, alpha 1 | collagen, type V, alpha 1; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin | 0.902 |
COL11A1 | COL6A3 | ENSP00000359114 | ENSP00000295550 | collagen, type XI, alpha 1 | collagen, type VI, alpha 3; Collagen VI acts as a cell-binding protein | 0.912 |
COL11A1 | COL9A1 | ENSP00000359114 | ENSP00000349790 | collagen, type XI, alpha 1 | collagen, type IX, alpha 1 | 0.923 |
COL11A1 | COL9A2 | ENSP00000359114 | ENSP00000361834 | collagen, type XI, alpha 1 | collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye | 0.921 |
COL11A1 | COL9A3 | ENSP00000359114 | ENSP00000341640 | collagen, type XI, alpha 1 | collagen, type IX, alpha 3; Structural component of hyaline cartilage and vitreous of the eye | 0.920 |
COL16A1 | COL11A1 | ENSP00000362776 | ENSP00000359114 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type XI, alpha 1 | 0.925 |
COL16A1 | COL2A1 | ENSP00000362776 | ENSP00000369889 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type II, alpha 1 | 0.920 |
COL16A1 | COL3A1 | ENSP00000362776 | ENSP00000304408 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type III, alpha 1 | 0.935 |
COL16A1 | COL5A1 | ENSP00000362776 | ENSP00000360882 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type V, alpha 1; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin | 0.949 |
COL16A1 | COL6A3 | ENSP00000362776 | ENSP00000295550 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type VI, alpha 3; Collagen VI acts as a cell-binding protein | 0.916 |
COL16A1 | COL9A1 | ENSP00000362776 | ENSP00000349790 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type IX, alpha 1 | 0.917 |
COL16A1 | COL9A2 | ENSP00000362776 | ENSP00000361834 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye | 0.906 |
COL16A1 | COL9A3 | ENSP00000362776 | ENSP00000341640 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | collagen, type IX, alpha 3; Structural component of hyaline cartilage and vitreous of the eye | 0.924 |
COL16A1 | MMP2 | ENSP00000362776 | ENSP00000219070 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative s [...] | 0.920 |
COL16A1 | MMP9 | ENSP00000362776 | ENSP00000361405 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide | 0.909 |
COL2A1 | COL11A1 | ENSP00000369889 | ENSP00000359114 | collagen, type II, alpha 1 | collagen, type XI, alpha 1 | 0.928 |
COL2A1 | COL16A1 | ENSP00000369889 | ENSP00000362776 | collagen, type II, alpha 1 | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | 0.920 |