RIOK3 protein (Homo sapiens) - STRING network view

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Score

RIOK3

RIO kinase 3 (yeast) (519 aa)

Predicted Functional Partners:

UBC

0.937

RIOK2

0.828

KRI1

0.736

MPHOSPH10

0.734

PES1

0.708

PPAN

0.694

ENSG00000243207

0.694

ESF1

0.678

AGAP10

0.648

NAT10

0.645

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP10	ENSG00000243207	ENSP00000407436	ENSP00000377385	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	PPAN-P2RY11 readthrough	0.736
AGAP10	ESF1	ENSP00000407436	ENSP00000202816	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	0.894
AGAP10	KRI1	ENSP00000407436	ENSP00000320917	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	KRI1 homolog (S. cerevisiae)	0.890
AGAP10	MPHOSPH10	ENSP00000407436	ENSP00000244230	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	0.979
AGAP10	NAT10	ENSP00000407436	ENSP00000257829	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	N-acetyltransferase 10 (GCN5-related); Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division	0.989
AGAP10	PES1	ENSP00000407436	ENSP00000346725	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome	0.906
AGAP10	PPAN	ENSP00000407436	ENSP00000450710	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	peter pan homolog (Drosophila); Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP	0.736
AGAP10	RIOK2	ENSP00000407436	ENSP00000283109	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	RIO kinase 2 (yeast)	0.402
AGAP10	RIOK3	ENSP00000407436	ENSP00000341874	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	RIO kinase 3 (yeast)	0.648
ENSG00000243207	AGAP10	ENSP00000377385	ENSP00000407436	PPAN-P2RY11 readthrough	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	0.736
ENSG00000243207	ESF1	ENSP00000377385	ENSP00000202816	PPAN-P2RY11 readthrough	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	0.810
ENSG00000243207	KRI1	ENSP00000377385	ENSP00000320917	PPAN-P2RY11 readthrough	KRI1 homolog (S. cerevisiae)	0.737
ENSG00000243207	MPHOSPH10	ENSP00000377385	ENSP00000244230	PPAN-P2RY11 readthrough	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing	0.837
ENSG00000243207	NAT10	ENSP00000377385	ENSP00000257829	PPAN-P2RY11 readthrough	N-acetyltransferase 10 (GCN5-related); Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization. Acetylates alpha-tubulin, which may affect microtubule stability and cell division	0.723
ENSG00000243207	PES1	ENSP00000377385	ENSP00000346725	PPAN-P2RY11 readthrough	pescadillo ribosomal biogenesis factor 1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome	0.926
ENSG00000243207	RIOK2	ENSP00000377385	ENSP00000283109	PPAN-P2RY11 readthrough	RIO kinase 2 (yeast)	0.518
ENSG00000243207	RIOK3	ENSP00000377385	ENSP00000341874	PPAN-P2RY11 readthrough	RIO kinase 3 (yeast)	0.694
ENSG00000243207	UBC	ENSP00000377385	ENSP00000344818	PPAN-P2RY11 readthrough	ubiquitin C	0.663
ESF1	AGAP10	ENSP00000202816	ENSP00000407436	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	ArfGAP with GTPase domain, ankyrin repeat and PH domain 10; Putative GTPase-activating protein (Potential)	0.894
ESF1	ENSG00000243207	ENSP00000202816	ENSP00000377385	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae); May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity)	PPAN-P2RY11 readthrough	0.810

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