SUMF2 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SUMF2

sulfatase modifying factor 2 (358 aa)

Predicted Functional Partners:

ARSH

0.963

ARSA

0.960

ARSI

0.955

STS

0.953

ARSB

0.953

ARSJ

0.952

ARSD

0.951

ARSF

0.951

ARSE

0.950

ARSK

0.947

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARSA	ARSB	ENSP00000216124	ENSP00000264914	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase B	0.936
ARSA	ARSD	ENSP00000216124	ENSP00000370546	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase D	0.923
ARSA	ARSE	ENSP00000216124	ENSP00000370526	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase E (chondrodysplasia punctata 1); May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates	0.916
ARSA	ARSF	ENSP00000216124	ENSP00000352319	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase F	0.917
ARSA	ARSH	ENSP00000216124	ENSP00000370522	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase family, member H	0.924
ARSA	ARSI	ENSP00000216124	ENSP00000333395	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase family, member I; Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts	0.928
ARSA	ARSJ	ENSP00000216124	ENSP00000320219	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase family, member J	0.928
ARSA	ARSK	ENSP00000216124	ENSP00000369346	arylsulfatase A; Hydrolyzes cerebroside sulfate	arylsulfatase family, member K	0.930
ARSA	STS	ENSP00000216124	ENSP00000217961	arylsulfatase A; Hydrolyzes cerebroside sulfate	steroid sulfatase (microsomal), isozyme S; Conversion of sulfated steroid precursors to estrogens during pregnancy	0.925
ARSA	SUMF2	ENSP00000216124	ENSP00000341938	arylsulfatase A; Hydrolyzes cerebroside sulfate	sulfatase modifying factor 2	0.960
ARSB	ARSA	ENSP00000264914	ENSP00000216124	arylsulfatase B	arylsulfatase A; Hydrolyzes cerebroside sulfate	0.936
ARSB	ARSD	ENSP00000264914	ENSP00000370546	arylsulfatase B	arylsulfatase D	0.925
ARSB	ARSE	ENSP00000264914	ENSP00000370526	arylsulfatase B	arylsulfatase E (chondrodysplasia punctata 1); May be essential for the correct composition of cartilage and bone matrix during development. Has no activity toward steroid sulfates	0.922
ARSB	ARSF	ENSP00000264914	ENSP00000352319	arylsulfatase B	arylsulfatase F	0.926
ARSB	ARSH	ENSP00000264914	ENSP00000370522	arylsulfatase B	arylsulfatase family, member H	0.941
ARSB	ARSI	ENSP00000264914	ENSP00000333395	arylsulfatase B	arylsulfatase family, member I; Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts	0.903
ARSB	ARSJ	ENSP00000264914	ENSP00000320219	arylsulfatase B	arylsulfatase family, member J	0.903
ARSB	ARSK	ENSP00000264914	ENSP00000369346	arylsulfatase B	arylsulfatase family, member K	0.972
ARSB	STS	ENSP00000264914	ENSP00000217961	arylsulfatase B	steroid sulfatase (microsomal), isozyme S; Conversion of sulfated steroid precursors to estrogens during pregnancy	0.931
ARSB	SUMF2	ENSP00000264914	ENSP00000341938	arylsulfatase B	sulfatase modifying factor 2	0.953

page 1 of 6

Databases

Neighborhood

Textmining

Fusion

Experiments

Cooccurrence

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About