NCR3 protein (Homo sapiens) - STRING network view

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Score

NCR3

natural cytotoxicity triggering receptor 3 (201 aa)

Predicted Functional Partners:

NCR3LG1

0.964

CD247

0.576

CD59

0.564

KLRF1

0.406

NCR1

0.405

KLRK1

0.402

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD247	NCR1	ENSP00000354782	ENSP00000291890	CD247 molecule; Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering	natural cytotoxicity triggering receptor 1	0.576
CD247	NCR3	ENSP00000354782	ENSP00000342156	CD247 molecule; Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering	natural cytotoxicity triggering receptor 3	0.576
CD59	NCR1	ENSP00000340210	ENSP00000291890	CD59 molecule, complement regulatory protein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase	natural cytotoxicity triggering receptor 1	0.564
CD59	NCR3	ENSP00000340210	ENSP00000342156	CD59 molecule, complement regulatory protein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase	natural cytotoxicity triggering receptor 3	0.564
KLRF1	KLRK1	ENSP00000279544	ENSP00000240618	killer cell lectin-like receptor subfamily F, member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts	killer cell lectin-like receptor subfamily K, member 1; Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes	0.838
KLRF1	NCR3	ENSP00000279544	ENSP00000342156	killer cell lectin-like receptor subfamily F, member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts	natural cytotoxicity triggering receptor 3	0.406
KLRF1	NCR3LG1	ENSP00000279544	ENSP00000341637	killer cell lectin-like receptor subfamily F, member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts	natural killer cell cytotoxicity receptor 3 ligand 1; Triggers NCR3-dependent natural killer cell activation	0.567
KLRK1	KLRF1	ENSP00000240618	ENSP00000279544	killer cell lectin-like receptor subfamily K, member 1; Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes	killer cell lectin-like receptor subfamily F, member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts	0.838
KLRK1	NCR1	ENSP00000240618	ENSP00000291890	killer cell lectin-like receptor subfamily K, member 1; Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes	natural cytotoxicity triggering receptor 1	0.424
KLRK1	NCR3	ENSP00000240618	ENSP00000342156	killer cell lectin-like receptor subfamily K, member 1; Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes	natural cytotoxicity triggering receptor 3	0.402
NCR1	CD247	ENSP00000291890	ENSP00000354782	natural cytotoxicity triggering receptor 1	CD247 molecule; Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering	0.576
NCR1	CD59	ENSP00000291890	ENSP00000340210	natural cytotoxicity triggering receptor 1	CD59 molecule, complement regulatory protein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase	0.564
NCR1	KLRK1	ENSP00000291890	ENSP00000240618	natural cytotoxicity triggering receptor 1	killer cell lectin-like receptor subfamily K, member 1; Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes	0.424
NCR1	NCR3	ENSP00000291890	ENSP00000342156	natural cytotoxicity triggering receptor 1	natural cytotoxicity triggering receptor 3	0.405
NCR3	CD247	ENSP00000342156	ENSP00000354782	natural cytotoxicity triggering receptor 3	CD247 molecule; Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering	0.576
NCR3	CD59	ENSP00000342156	ENSP00000340210	natural cytotoxicity triggering receptor 3	CD59 molecule, complement regulatory protein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase	0.564
NCR3	KLRF1	ENSP00000342156	ENSP00000279544	natural cytotoxicity triggering receptor 3	killer cell lectin-like receptor subfamily F, member 1; Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts	0.406
NCR3	KLRK1	ENSP00000342156	ENSP00000240618	natural cytotoxicity triggering receptor 3	killer cell lectin-like receptor subfamily K, member 1; Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes	0.402
NCR3	NCR1	ENSP00000342156	ENSP00000291890	natural cytotoxicity triggering receptor 3	natural cytotoxicity triggering receptor 1	0.405
NCR3	NCR3LG1	ENSP00000342156	ENSP00000341637	natural cytotoxicity triggering receptor 3	natural killer cell cytotoxicity receptor 3 ligand 1; Triggers NCR3-dependent natural killer cell activation	0.964

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