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PTPN11 PTPN11 LCK LCK KIR2DL3 KIR2DL3 HLA-C HLA-C PTPN6 PTPN6
"KIR2DL3" - killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 in Homo sapiens
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KIR2DL3killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3; Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis (341 aa)    
Predicted Functional Partners:
HLA-C
major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) (366 aa)
        score_image score_image     0.982
PTPN11
protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity (593 aa)
        score_image score_image     0.911
LCK
lymphocyte-specific protein tyrosine kinase (509 aa)
        score_image       0.576
PTPN6
protein tyrosine phosphatase, non-receptor type 6; Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis (624 aa)
        score_image       0.564
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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