Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | ABCA9 | ATP-binding cassette, sub-family A (ABC1), member 9; May play a role in monocyte differentiation and lipid homeostasis (1624 aa) | ||||||||||||
Predicted Functional Partners:
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 | ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (655 aa) |
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0.619 | ||||||
 | ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B (By similarity) (709 aa) |
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0.561 | ||||||||||
 | ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (1527 aa) |
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0.543 | |||||||||
 | ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 (634 aa) |
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0.533 | ||||||||||
 | ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (1549 aa) |
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0.512 | |||||||||
 | OR56B4 | olfactory receptor, family 56, subfamily B, member 4; Odorant receptor (Potential) (319 aa) |
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0.509 | ||||||||||
 | TNNI1 | troponin I type 1 (skeletal, slow) (187 aa) |
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0.497 | ||||||||||
 | SRRM1 | serine/arginine repetitive matrix 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3’-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequen [...] (904 aa) |
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0.483 | ||||||||||
 | ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 (845 aa) |
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0.453 | ||||||||||
 | HIST2H2AB | histone cluster 2, H2ab (130 aa) |
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0.441 | |||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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