SAMD11 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SAMD11

sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity) (681 aa)

Predicted Functional Partners:

ZNF799

0.472

FAM102B

0.471

ZNF598

0.459

URGCP

0.459

TAMM41

0.457

TAS2R13

0.453

ACTRT1

0.414

NDUFAF7

0.412

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTRT1	FAM102B	ENSP00000360165	ENSP00000359052	actin-related protein T1	family with sequence similarity 102, member B	0.418
ACTRT1	SAMD11	ENSP00000360165	ENSP00000342313	actin-related protein T1	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	0.414
ACTRT1	ZNF799	ENSP00000360165	ENSP00000411084	actin-related protein T1	zinc finger protein 799; May be involved in transcriptional regulation	0.555
FAM102B	ACTRT1	ENSP00000359052	ENSP00000360165	family with sequence similarity 102, member B	actin-related protein T1	0.418
FAM102B	SAMD11	ENSP00000359052	ENSP00000342313	family with sequence similarity 102, member B	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	0.471
FAM102B	ZNF799	ENSP00000359052	ENSP00000411084	family with sequence similarity 102, member B	zinc finger protein 799; May be involved in transcriptional regulation	0.480
NDUFAF7	SAMD11	ENSP00000002125	ENSP00000342313	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	0.412
NDUFAF7	TAMM41	ENSP00000002125	ENSP00000273037	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity)	0.722
NDUFAF7	TAS2R13	ENSP00000002125	ENSP00000375095	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	taste receptor, type 2, member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5	0.406
NDUFAF7	URGCP	ENSP00000002125	ENSP00000396918	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer	0.412
NDUFAF7	ZNF598	ENSP00000002125	ENSP00000411409	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	zinc finger protein 598	0.408
SAMD11	ACTRT1	ENSP00000342313	ENSP00000360165	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	actin-related protein T1	0.414
SAMD11	FAM102B	ENSP00000342313	ENSP00000359052	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	family with sequence similarity 102, member B	0.471
SAMD11	NDUFAF7	ENSP00000342313	ENSP00000002125	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	0.412
SAMD11	TAMM41	ENSP00000342313	ENSP00000273037	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity)	0.457
SAMD11	TAS2R13	ENSP00000342313	ENSP00000375095	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	taste receptor, type 2, member 13; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5	0.453
SAMD11	URGCP	ENSP00000342313	ENSP00000396918	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	upregulator of cell proliferation; May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer	0.459
SAMD11	ZNF598	ENSP00000342313	ENSP00000411409	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	zinc finger protein 598	0.459
SAMD11	ZNF799	ENSP00000342313	ENSP00000411084	sterile alpha motif domain containing 11; May play a role in photoreceptor development (By similarity)	zinc finger protein 799; May be involved in transcriptional regulation	0.472
TAMM41	NDUFAF7	ENSP00000273037	ENSP00000002125	TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity)	NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I)	0.722

page 1 of 3

Experiments

Cooccurrence

Textmining

Neighborhood

Coexpression

Fusion

Databases

© STRING Consortium 2017

Credits

Access

Info

About