node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCY4 | ADCY7 | ENSP00000312126 | ENSP00000254235 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | 0.904 |
ADCY4 | DRD2 | ENSP00000312126 | ENSP00000354859 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | 0.906 |
ADCY4 | GRM2 | ENSP00000312126 | ENSP00000378492 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | glutamate receptor, metabotropic 2; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization | 0.905 |
ADCY4 | GRM3 | ENSP00000312126 | ENSP00000355316 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | glutamate receptor, metabotropic 3; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.905 |
ADCY4 | GRM4 | ENSP00000312126 | ENSP00000363296 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | glutamate receptor, metabotropic 4; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.905 |
ADCY4 | GRM7 | ENSP00000312126 | ENSP00000350348 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | glutamate receptor, metabotropic 7; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.905 |
ADCY4 | GRM8 | ENSP00000312126 | ENSP00000344173 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | glutamate receptor, metabotropic 8 | 0.905 |
ADCY4 | HRH3 | ENSP00000312126 | ENSP00000342560 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | histamine receptor H3; The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization | 0.914 |
ADCY4 | MCHR1 | ENSP00000312126 | ENSP00000249016 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis | 0.900 |
ADCY4 | TAS2R40 | ENSP00000312126 | ENSP00000386210 | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | taste receptor, type 2, member 40; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 | 0.900 |
ADCY7 | ADCY4 | ENSP00000254235 | ENSP00000312126 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By similarity) | 0.904 |
ADCY7 | DRD2 | ENSP00000254235 | ENSP00000354859 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) | 0.906 |
ADCY7 | GRM2 | ENSP00000254235 | ENSP00000378492 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | glutamate receptor, metabotropic 2; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization | 0.905 |
ADCY7 | GRM3 | ENSP00000254235 | ENSP00000355316 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | glutamate receptor, metabotropic 3; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.905 |
ADCY7 | GRM4 | ENSP00000254235 | ENSP00000363296 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | glutamate receptor, metabotropic 4; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.905 |
ADCY7 | GRM7 | ENSP00000254235 | ENSP00000350348 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | glutamate receptor, metabotropic 7; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.905 |
ADCY7 | GRM8 | ENSP00000254235 | ENSP00000344173 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | glutamate receptor, metabotropic 8 | 0.905 |
ADCY7 | HRH3 | ENSP00000254235 | ENSP00000342560 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | histamine receptor H3; The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization | 0.913 |
ADCY7 | MCHR1 | ENSP00000254235 | ENSP00000249016 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | melanin-concentrating hormone receptor 1; Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis | 0.900 |
ADCY7 | TAS2R40 | ENSP00000254235 | ENSP00000386210 | adenylate cyclase 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase | taste receptor, type 2, member 40; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 | 0.900 |