KRT77 protein (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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second shell of interactors

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

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Score

KRT77

keratin 77 (578 aa)

Predicted Functional Partners:

UBC

0.856

USP32

0.740

USP53

0.740

AP2M1

0.499

LCE2D

0.407

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2M1	KRT77	ENSP00000292807	ENSP00000342710	adaptor-related protein complex 2, mu 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a [...]	keratin 77	0.499
AP2M1	UBC	ENSP00000292807	ENSP00000344818	adaptor-related protein complex 2, mu 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a [...]	ubiquitin C	0.979
KRT77	AP2M1	ENSP00000342710	ENSP00000292807	keratin 77	adaptor-related protein complex 2, mu 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a [...]	0.499
KRT77	LCE2D	ENSP00000342710	ENSP00000357773	keratin 77	late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum	0.407
KRT77	UBC	ENSP00000342710	ENSP00000344818	keratin 77	ubiquitin C	0.856
KRT77	USP32	ENSP00000342710	ENSP00000300896	keratin 77	ubiquitin specific peptidase 32	0.740
KRT77	USP53	ENSP00000342710	ENSP00000274030	keratin 77	ubiquitin specific peptidase 53; Has no peptidase activity	0.740
LCE2D	KRT77	ENSP00000357773	ENSP00000342710	late cornified envelope 2D; Precursors of the cornified envelope of the stratum corneum	keratin 77	0.407
UBC	AP2M1	ENSP00000344818	ENSP00000292807	ubiquitin C	adaptor-related protein complex 2, mu 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a [...]	0.979
UBC	KRT77	ENSP00000344818	ENSP00000342710	ubiquitin C	keratin 77	0.856
UBC	USP32	ENSP00000344818	ENSP00000300896	ubiquitin C	ubiquitin specific peptidase 32	0.754
USP32	KRT77	ENSP00000300896	ENSP00000342710	ubiquitin specific peptidase 32	keratin 77	0.740
USP32	UBC	ENSP00000300896	ENSP00000344818	ubiquitin specific peptidase 32	ubiquitin C	0.754
USP53	KRT77	ENSP00000274030	ENSP00000342710	ubiquitin specific peptidase 53; Has no peptidase activity	keratin 77	0.740

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