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GPATCH8 GPATCH8 ECD ECD KDM2A KDM2A UBC UBC ZNF791 ZNF791 XRN1 XRN1 FBXL19 FBXL19 EIF4E1B EIF4E1B KPNA7 KPNA7 TUBAL3 TUBAL3 OR51B4 OR51B4
"ZNF791" - zinc finger protein 791 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZNF791zinc finger protein 791; May be involved in transcriptional regulation (576 aa)    
Predicted Functional Partners:
GPATCH8
G patch domain containing 8 (1502 aa)
            score_image   0.580
ECD
ecdysoneless homolog (Drosophila); Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes (677 aa)
            score_image   0.577
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.571
OR51B4
olfactory receptor, family 51, subfamily B, member 4; Odorant receptor (Potential) (310 aa)
            score_image   0.565
KPNA7
karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) (516 aa)
        score_image   score_image   0.549
TUBAL3
tubulin, alpha-like 3 (446 aa)
        score_image   score_image   0.548
XRN1
5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) (1706 aa)
      score_image score_image   score_image   0.543
EIF4E1B
eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) (242 aa)
            score_image   0.504
KDM2A
lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] (1162 aa)
        score_image   score_image   0.501
FBXL19
F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) (694 aa)
        score_image   score_image   0.501
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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