node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ECD | UBC | ENSP00000401566 | ENSP00000344818 | ecdysoneless homolog (Drosophila); Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes | ubiquitin C | 0.728 |
ECD | ZNF791 | ENSP00000401566 | ENSP00000342974 | ecdysoneless homolog (Drosophila); Novel regulator of p53 stability and function. May also be a transcriptional activator required for the expression of glycolytic genes | zinc finger protein 791; May be involved in transcriptional regulation | 0.577 |
EIF4E1B | KPNA7 | ENSP00000323714 | ENSP00000330878 | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) | 0.416 |
EIF4E1B | OR51B4 | ENSP00000323714 | ENSP00000369573 | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | olfactory receptor, family 51, subfamily B, member 4; Odorant receptor (Potential) | 0.505 |
EIF4E1B | TUBAL3 | ENSP00000323714 | ENSP00000369784 | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | tubulin, alpha-like 3 | 0.553 |
EIF4E1B | UBC | ENSP00000323714 | ENSP00000344818 | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | ubiquitin C | 0.441 |
EIF4E1B | XRN1 | ENSP00000323714 | ENSP00000264951 | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | 5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) | 0.738 |
EIF4E1B | ZNF791 | ENSP00000323714 | ENSP00000342974 | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | zinc finger protein 791; May be involved in transcriptional regulation | 0.504 |
FBXL19 | ZNF791 | ENSP00000369666 | ENSP00000342974 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 791; May be involved in transcriptional regulation | 0.501 |
GPATCH8 | UBC | ENSP00000467556 | ENSP00000344818 | G patch domain containing 8 | ubiquitin C | 0.620 |
GPATCH8 | ZNF791 | ENSP00000467556 | ENSP00000342974 | G patch domain containing 8 | zinc finger protein 791; May be involved in transcriptional regulation | 0.580 |
KDM2A | UBC | ENSP00000432786 | ENSP00000344818 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | ubiquitin C | 0.740 |
KDM2A | ZNF791 | ENSP00000432786 | ENSP00000342974 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 791; May be involved in transcriptional regulation | 0.501 |
KPNA7 | EIF4E1B | ENSP00000330878 | ENSP00000323714 | karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | 0.416 |
KPNA7 | OR51B4 | ENSP00000330878 | ENSP00000369573 | karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) | olfactory receptor, family 51, subfamily B, member 4; Odorant receptor (Potential) | 0.501 |
KPNA7 | TUBAL3 | ENSP00000330878 | ENSP00000369784 | karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) | tubulin, alpha-like 3 | 0.472 |
KPNA7 | ZNF791 | ENSP00000330878 | ENSP00000342974 | karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) | zinc finger protein 791; May be involved in transcriptional regulation | 0.549 |
OR51B4 | EIF4E1B | ENSP00000369573 | ENSP00000323714 | olfactory receptor, family 51, subfamily B, member 4; Odorant receptor (Potential) | eukaryotic translation initiation factor 4E family member 1B; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure (By similarity) | 0.505 |
OR51B4 | KPNA7 | ENSP00000369573 | ENSP00000330878 | olfactory receptor, family 51, subfamily B, member 4; Odorant receptor (Potential) | karyopherin alpha 7 (importin alpha 8); Functions in nuclear protein import (By similarity) | 0.501 |
OR51B4 | TUBAL3 | ENSP00000369573 | ENSP00000369784 | olfactory receptor, family 51, subfamily B, member 4; Odorant receptor (Potential) | tubulin, alpha-like 3 | 0.539 |