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STRINGSTRING
SFI1 SFI1 TTC28 TTC28 C22orf23 C22orf23 KIAA1671 KIAA1671 SLC17A4 SLC17A4 CCDC157 CCDC157 KIAA1644 KIAA1644 MORC2 MORC2 EFCAB6 EFCAB6 POLR3H POLR3H ALS2CR8 ALS2CR8
"CCDC157" - coiled-coil domain containing 157 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
CCDC157coiled-coil domain containing 157 (752 aa)    
Predicted Functional Partners:
KIAA1644
KIAA1644 (199 aa)
            score_image   0.649
MORC2
MORC family CW-type zinc finger 2; May act as a transcriptional repressor. Down-regulates CA9 expression (970 aa)
            score_image   0.578
C22orf23
chromosome 22 open reading frame 23 (217 aa)
        score_image       0.574
SLC17A4
solute carrier family 17 (sodium phosphate), member 4; May be involved in actively transporting phosphate into cells via Na(+) cotransport (By similarity) (497 aa)
            score_image   0.510
EFCAB6
EF-hand calcium binding domain 6 (1501 aa)
            score_image   0.508
TTC28
tetratricopeptide repeat domain 28 (2481 aa)
            score_image   0.506
ALS2CR8
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; May be a transcription factor (By similarity) (725 aa)
            score_image   0.472
SFI1
Sfi1 homolog, spindle assembly associated (yeast) (1242 aa)
            score_image   0.431
KIAA1671
KIAA1671 (1806 aa)
            score_image   0.418
POLR3H
polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcrip [...] (204 aa)
            score_image   0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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