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STRINGSTRING
SUV39H2 SUV39H2 SLC5A10 SLC5A10 CSNK1A1 CSNK1A1 PNPLA1 PNPLA1 FAM83G FAM83G CHD6 CHD6 CSNK1A1L CSNK1A1L OSGEP OSGEP TP53RK TP53RK
"FAM83G" - family with sequence similarity 83, member G in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM83Gfamily with sequence similarity 83, member G (823 aa)    
Predicted Functional Partners:
CHD6
chromodomain helicase DNA binding protein 6 (2715 aa)
            score_image   0.578
TP53RK
TP53 regulating kinase; Protein kinase that phosphorylates ’Ser-15’ of p53/TP53 protein and may therefore participate in its activation (253 aa)
            score_image   0.576
OSGEP
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) (335 aa)
            score_image   0.539
CSNK1A1
casein kinase 1, alpha 1 (365 aa)
        score_image   score_image   0.527
PNPLA1
patatin-like phospholipase domain containing 1; Lipid hydrolase (By similarity) (532 aa)
            score_image   0.438
CSNK1A1L
casein kinase 1, alpha 1-like; Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity) (337 aa)
            score_image   0.434
SUV39H2
suppressor of variegation 3-9 homolog 2 (Drosophila); Histone methyltransferase that specifically trimethylates ’Lys-9’ of histone H3 using monomethylated H3 ’Lys- 9’ as substrate. H3 ’Lys-9’ trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 ’Lys-9’ trimethylation is also required to direct DNA methylation at per [...] (410 aa)
            score_image   0.423
SLC5A10
solute carrier family 5 (sodium/glucose cotransporter), member 10; High capacity transporter for mannose and fructose and, to a lesser extent, glucose, AMG, and galactose (612 aa)
            score_image   0.408
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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