node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMBP | MEST | ENSP00000265132 | ENSP00000223215 | alpha-1-microglobulin/bikunin precursor; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization | mesoderm specific transcript homolog (mouse) | 0.580 |
AMBP | SH3GL1 | ENSP00000265132 | ENSP00000269886 | alpha-1-microglobulin/bikunin precursor; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | 0.567 |
AMBP | SULT1A3 | ENSP00000265132 | ENSP00000343645 | alpha-1-microglobulin/bikunin precursor; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.414 |
BTF3 | SULT1A3 | ENSP00000369965 | ENSP00000343645 | basic transcription factor 3; General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.566 |
BTF3 | UBC | ENSP00000369965 | ENSP00000344818 | basic transcription factor 3; General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription | ubiquitin C | 0.947 |
COPA | SULT1A3 | ENSP00000357048 | ENSP00000343645 | coatomer protein complex, subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the [...] | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.806 |
COPA | UBC | ENSP00000357048 | ENSP00000344818 | coatomer protein complex, subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the [...] | ubiquitin C | 0.997 |
MEST | AMBP | ENSP00000223215 | ENSP00000265132 | mesoderm specific transcript homolog (mouse) | alpha-1-microglobulin/bikunin precursor; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization | 0.580 |
MEST | SULT1A3 | ENSP00000223215 | ENSP00000343645 | mesoderm specific transcript homolog (mouse) | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.457 |
PROC | SULT1A3 | ENSP00000234071 | ENSP00000343645 | protein C (inactivator of coagulation factors Va and VIIIa); Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.471 |
PROC | VWF | ENSP00000234071 | ENSP00000261405 | protein C (inactivator of coagulation factors Va and VIIIa); Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids | von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma | 0.819 |
SH3GL1 | AMBP | ENSP00000269886 | ENSP00000265132 | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | alpha-1-microglobulin/bikunin precursor; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization | 0.567 |
SH3GL1 | SULT1A3 | ENSP00000269886 | ENSP00000343645 | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.416 |
SH3GL1 | UBC | ENSP00000269886 | ENSP00000344818 | SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | ubiquitin C | 0.731 |
SHMT1 | SULT1A3 | ENSP00000318868 | ENSP00000343645 | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | 0.559 |
SHMT1 | UBC | ENSP00000318868 | ENSP00000344818 | serine hydroxymethyltransferase 1 (soluble); Interconversion of serine and glycine (By similarity) | ubiquitin C | 0.984 |
SULT1A3 | AMBP | ENSP00000343645 | ENSP00000265132 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | alpha-1-microglobulin/bikunin precursor; Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization | 0.414 |
SULT1A3 | BTF3 | ENSP00000343645 | ENSP00000369965 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | basic transcription factor 3; General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription | 0.566 |
SULT1A3 | COPA | ENSP00000343645 | ENSP00000357048 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | coatomer protein complex, subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the [...] | 0.806 |
SULT1A3 | MEST | ENSP00000343645 | ENSP00000223215 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs | mesoderm specific transcript homolog (mouse) | 0.457 |