node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACA | ACACB | ENSP00000344789 | ENSP00000341044 | acetyl-CoA carboxylase alpha | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.999 |
ACACA | BTD | ENSP00000344789 | ENSP00000306477 | acetyl-CoA carboxylase alpha | biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation | 0.645 |
ACACA | CAD | ENSP00000344789 | ENSP00000264705 | acetyl-CoA carboxylase alpha | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.988 |
ACACA | IVD | ENSP00000344789 | ENSP00000418397 | acetyl-CoA carboxylase alpha | isovaleryl-CoA dehydrogenase | 0.589 |
ACACA | MCCC1 | ENSP00000344789 | ENSP00000265594 | acetyl-CoA carboxylase alpha | methylcrotonoyl-CoA carboxylase 1 (alpha) | 0.841 |
ACACA | MCCC2 | ENSP00000344789 | ENSP00000343657 | acetyl-CoA carboxylase alpha | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.860 |
ACACA | MUT | ENSP00000344789 | ENSP00000274813 | acetyl-CoA carboxylase alpha | methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species | 0.855 |
ACACA | PCCA | ENSP00000344789 | ENSP00000365462 | acetyl-CoA carboxylase alpha | propionyl CoA carboxylase, alpha polypeptide | 0.839 |
ACACB | ACACA | ENSP00000341044 | ENSP00000344789 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acetyl-CoA carboxylase alpha | 0.999 |
ACACB | BTD | ENSP00000341044 | ENSP00000306477 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation | 0.472 |
ACACB | CAD | ENSP00000341044 | ENSP00000264705 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.988 |
ACACB | IVD | ENSP00000341044 | ENSP00000418397 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | isovaleryl-CoA dehydrogenase | 0.632 |
ACACB | MCCC1 | ENSP00000341044 | ENSP00000265594 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | methylcrotonoyl-CoA carboxylase 1 (alpha) | 0.824 |
ACACB | MCCC2 | ENSP00000341044 | ENSP00000343657 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.866 |
ACACB | MUT | ENSP00000341044 | ENSP00000274813 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species | 0.854 |
ACACB | PCCA | ENSP00000341044 | ENSP00000365462 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | propionyl CoA carboxylase, alpha polypeptide | 0.826 |
BTD | ACACA | ENSP00000306477 | ENSP00000344789 | biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation | acetyl-CoA carboxylase alpha | 0.645 |
BTD | ACACB | ENSP00000306477 | ENSP00000341044 | biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.472 |
BTD | MCCC1 | ENSP00000306477 | ENSP00000265594 | biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation | methylcrotonoyl-CoA carboxylase 1 (alpha) | 0.772 |
BTD | MCCC2 | ENSP00000306477 | ENSP00000343657 | biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.763 |