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MCC MCC MUT MUT MCCC1 MCCC1 ACACB ACACB IVD IVD MCCC2 MCCC2 PCCA PCCA ACACA ACACA USHBP1 USHBP1 BTD BTD CAD CAD
"MCCC2" - methylcrotonoyl-CoA carboxylase 2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Gene Fusion
Cooccurence
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Experiments
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Textmining
[Homology]
Score
MCCC2methylcrotonoyl-CoA carboxylase 2 (beta) (563 aa)    
Predicted Functional Partners:
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha) (725 aa)
score_image score_image   score_image score_image   score_image   0.991
PCCA
propionyl CoA carboxylase, alpha polypeptide (728 aa)
score_image score_image   score_image score_image   score_image   0.959
USHBP1
Usher syndrome 1C binding protein 1 (703 aa)
            score_image   0.888
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
score_image       score_image   score_image   0.866
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
score_image       score_image   score_image   0.860
MCC
mutated in colorectal cancers; Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b- catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation (1019 aa)
            score_image   0.860
MUT
methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species (750 aa)
score_image           score_image   0.823
IVD
isovaleryl-CoA dehydrogenase (426 aa)
    score_image score_image     score_image   0.786
BTD
biotinidase; Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation (543 aa)
            score_image   0.763
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa)
      score_image score_image       0.736
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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