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STRINGSTRING
WIPI2 WIPI2 HIGD2A HIGD2A PCDHA12 PCDHA12 BTBD8 BTBD8 TMEM54 TMEM54 TSSK3 TSSK3 CCDC28B CCDC28B
"BTBD8" - BTB in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTBD8BTB (POZ) domain containing 8 (378 aa)    
Predicted Functional Partners:
CCDC28B
coiled-coil domain containing 28B; Involved in ciliogenesis (200 aa)
            score_image   0.536
TMEM54
transmembrane protein 54 (222 aa)
            score_image   0.501
TSSK3
testis-specific serine kinase 3; May be involved in a signaling pathway during male germ cell development or mature sperm function (268 aa)
            score_image   0.459
WIPI2
WD repeat domain, phosphoinositide interacting 2; Probable early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to PtdIns3P. May bind PtdIns3P (454 aa)
        score_image       0.445
PCDHA12
protocadherin alpha 12; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain (941 aa)
            score_image   0.416
HIGD2A
HIG1 hypoxia inducible domain family, member 2A; Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes (106 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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