ZNF683 protein (Homo sapiens) - STRING network view

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ZNF683

zinc finger protein 683; May be involved in transcriptional regulation (504 aa)

Predicted Functional Partners:

TMC5

0.777

OR7G2

0.704

FAM150A

0.650

KDM1A

0.639

MAOB

0.638

MAOA

0.638

KDM1B

0.638

SPATS1

0.633

UNC5C

0.610

UNC5D

0.610

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM150A	OR7G2	ENSP00000351345	ENSP00000303822	family with sequence similarity 150, member A	olfactory receptor, family 7, subfamily G, member 2; Odorant receptor (Potential)	0.654
FAM150A	ZNF683	ENSP00000351345	ENSP00000344095	family with sequence similarity 150, member A	zinc finger protein 683; May be involved in transcriptional regulation	0.650
KDM1A	ZNF683	ENSP00000383042	ENSP00000344095	lysine (K)-specific demethylase 1A	zinc finger protein 683; May be involved in transcriptional regulation	0.639
KDM1B	ZNF683	ENSP00000297792	ENSP00000344095	lysine (K)-specific demethylase 1B; Histone demethylase that demethylates ’Lys-4’ of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated ’Lys-4’ of histone H3. Has no effect on tri- methylated ’Lys-4’, mono-, di- or tri-methylated ’Lys-9’, mono-, di- or tri-methylated ’Lys-27’, mono-, di- or tri-methylat [...]	zinc finger protein 683; May be involved in transcriptional regulation	0.638
MAOA	ZNF683	ENSP00000340684	ENSP00000344095	monoamine oxidase A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine	zinc finger protein 683; May be involved in transcriptional regulation	0.638
MAOB	ZNF683	ENSP00000367309	ENSP00000344095	monoamine oxidase B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine	zinc finger protein 683; May be involved in transcriptional regulation	0.638
OR7G2	FAM150A	ENSP00000303822	ENSP00000351345	olfactory receptor, family 7, subfamily G, member 2; Odorant receptor (Potential)	family with sequence similarity 150, member A	0.654
OR7G2	ZNF683	ENSP00000303822	ENSP00000344095	olfactory receptor, family 7, subfamily G, member 2; Odorant receptor (Potential)	zinc finger protein 683; May be involved in transcriptional regulation	0.704
SPATS1	TMC5	ENSP00000424400	ENSP00000379531	spermatogenesis associated, serine-rich 1	transmembrane channel-like 5; Probable ion channel (By similarity)	0.624
SPATS1	ZNF683	ENSP00000424400	ENSP00000344095	spermatogenesis associated, serine-rich 1	zinc finger protein 683; May be involved in transcriptional regulation	0.633
TMC5	SPATS1	ENSP00000379531	ENSP00000424400	transmembrane channel-like 5; Probable ion channel (By similarity)	spermatogenesis associated, serine-rich 1	0.624
TMC5	ZNF683	ENSP00000379531	ENSP00000344095	transmembrane channel-like 5; Probable ion channel (By similarity)	zinc finger protein 683; May be involved in transcriptional regulation	0.777
UNC5C	UNC5D	ENSP00000406022	ENSP00000385143	unc-5 homolog C (C. elegans); Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity)	unc-5 homolog D (C. elegans); Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity)	0.903
UNC5C	ZNF683	ENSP00000406022	ENSP00000344095	unc-5 homolog C (C. elegans); Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity)	zinc finger protein 683; May be involved in transcriptional regulation	0.610
UNC5D	UNC5C	ENSP00000385143	ENSP00000406022	unc-5 homolog D (C. elegans); Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity)	unc-5 homolog C (C. elegans); Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity)	0.903
UNC5D	ZNF683	ENSP00000385143	ENSP00000344095	unc-5 homolog D (C. elegans); Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity)	zinc finger protein 683; May be involved in transcriptional regulation	0.610
ZNF683	FAM150A	ENSP00000344095	ENSP00000351345	zinc finger protein 683; May be involved in transcriptional regulation	family with sequence similarity 150, member A	0.650
ZNF683	KDM1A	ENSP00000344095	ENSP00000383042	zinc finger protein 683; May be involved in transcriptional regulation	lysine (K)-specific demethylase 1A	0.639
ZNF683	KDM1B	ENSP00000344095	ENSP00000297792	zinc finger protein 683; May be involved in transcriptional regulation	lysine (K)-specific demethylase 1B; Histone demethylase that demethylates ’Lys-4’ of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated ’Lys-4’ of histone H3. Has no effect on tri- methylated ’Lys-4’, mono-, di- or tri-methylated ’Lys-9’, mono-, di- or tri-methylated ’Lys-27’, mono-, di- or tri-methylat [...]	0.638
ZNF683	MAOA	ENSP00000344095	ENSP00000340684	zinc finger protein 683; May be involved in transcriptional regulation	monoamine oxidase A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine	0.638

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