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RNASEL RNASEL GLUD1 GLUD1 ANGPT4 ANGPT4 GLUD2 GLUD2 RNASE1 RNASE1 RNH1 RNH1 RNASE11 RNASE11 TMEM110 TMEM110
"RNASE1" - ribonuclease, RNase A family, 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
RNASE1ribonuclease, RNase A family, 1 (pancreatic) (156 aa)    
Predicted Functional Partners:
RNH1
ribonuclease/angiogenin inhibitor 1; Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis (461 aa)
        score_image   score_image   0.982
GLUD1
glutamate dehydrogenase 1; May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity) (558 aa)
            score_image   0.746
GLUD2
glutamate dehydrogenase 2; Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission (558 aa)
            score_image   0.689
RNASEL
ribonuclease L (2’,5’-oligoisoadenylate synthetase-dependent); Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress- response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosi [...] (741 aa)
            score_image   0.659
RNASE11
ribonuclease, RNase A family, 11 (non-active) (199 aa)
            score_image   0.501
ANGPT4
angiopoietin 4; Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis (503 aa)
            score_image   0.457
TMEM110
transmembrane protein 110 (294 aa)
            score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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