FOCAD protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FOCAD

focadhesin; Potential tumor suppressor in gliomas (By similarity) (1801 aa)

Predicted Functional Partners:

UBC

0.849

PTPLAD2

0.617

TMEM56

0.570

CCAR1

0.542

LRRC9

0.503

CDRT4

0.472

OR56B4

0.468

DMRTA1

0.450

TMEM161B

0.450

COMMD7

0.420

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCAR1	FOCAD	ENSP00000265872	ENSP00000344307	cell division cycle and apoptosis regulator 1	focadhesin; Potential tumor suppressor in gliomas (By similarity)	0.542
CCAR1	UBC	ENSP00000265872	ENSP00000344818	cell division cycle and apoptosis regulator 1	ubiquitin C	0.826
CDRT4	FOCAD	ENSP00000310031	ENSP00000344307	CMT1A duplicated region transcript 4	focadhesin; Potential tumor suppressor in gliomas (By similarity)	0.472
CDRT4	LRRC9	ENSP00000310031	ENSP00000454748	CMT1A duplicated region transcript 4	leucine rich repeat containing 9	0.567
COMMD7	FOCAD	ENSP00000278980	ENSP00000344307	COMM domain containing 7; Associates with the NF-kappa-B complex and suppresses its transcriptional activity	focadhesin; Potential tumor suppressor in gliomas (By similarity)	0.420
COMMD7	TMEM56	ENSP00000278980	ENSP00000359222	COMM domain containing 7; Associates with the NF-kappa-B complex and suppresses its transcriptional activity	transmembrane protein 56	0.691
DMRTA1	FOCAD	ENSP00000319651	ENSP00000344307	DMRT-like family A1	focadhesin; Potential tumor suppressor in gliomas (By similarity)	0.450
DMRTA1	PTPLAD2	ENSP00000319651	ENSP00000419503	DMRT-like family A1	protein tyrosine phosphatase-like A domain containing 2; Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis	0.492
FOCAD	CCAR1	ENSP00000344307	ENSP00000265872	focadhesin; Potential tumor suppressor in gliomas (By similarity)	cell division cycle and apoptosis regulator 1	0.542
FOCAD	CDRT4	ENSP00000344307	ENSP00000310031	focadhesin; Potential tumor suppressor in gliomas (By similarity)	CMT1A duplicated region transcript 4	0.472
FOCAD	COMMD7	ENSP00000344307	ENSP00000278980	focadhesin; Potential tumor suppressor in gliomas (By similarity)	COMM domain containing 7; Associates with the NF-kappa-B complex and suppresses its transcriptional activity	0.420
FOCAD	DMRTA1	ENSP00000344307	ENSP00000319651	focadhesin; Potential tumor suppressor in gliomas (By similarity)	DMRT-like family A1	0.450
FOCAD	LRRC9	ENSP00000344307	ENSP00000454748	focadhesin; Potential tumor suppressor in gliomas (By similarity)	leucine rich repeat containing 9	0.503
FOCAD	OR56B4	ENSP00000344307	ENSP00000321196	focadhesin; Potential tumor suppressor in gliomas (By similarity)	olfactory receptor, family 56, subfamily B, member 4; Odorant receptor (Potential)	0.468
FOCAD	PTPLAD2	ENSP00000344307	ENSP00000419503	focadhesin; Potential tumor suppressor in gliomas (By similarity)	protein tyrosine phosphatase-like A domain containing 2; Responsible for the dehydration step in very long-chain fatty acid (VLCFA) synthesis	0.617
FOCAD	TMEM161B	ENSP00000344307	ENSP00000296595	focadhesin; Potential tumor suppressor in gliomas (By similarity)	transmembrane protein 161B	0.450
FOCAD	TMEM56	ENSP00000344307	ENSP00000359222	focadhesin; Potential tumor suppressor in gliomas (By similarity)	transmembrane protein 56	0.570
FOCAD	UBC	ENSP00000344307	ENSP00000344818	focadhesin; Potential tumor suppressor in gliomas (By similarity)	ubiquitin C	0.849
LRRC9	CDRT4	ENSP00000454748	ENSP00000310031	leucine rich repeat containing 9	CMT1A duplicated region transcript 4	0.567
LRRC9	FOCAD	ENSP00000454748	ENSP00000344307	leucine rich repeat containing 9	focadhesin; Potential tumor suppressor in gliomas (By similarity)	0.503

page 1 of 2

Experiments

Cooccurrence

Textmining

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About