node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACA | ACACB | ENSP00000344789 | ENSP00000341044 | acetyl-CoA carboxylase alpha | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.999 |
ACACA | DHRS1 | ENSP00000344789 | ENSP00000288111 | acetyl-CoA carboxylase alpha | dehydrogenase/reductase (SDR family) member 1 | 0.581 |
ACACA | DHRS2 | ENSP00000344789 | ENSP00000344674 | acetyl-CoA carboxylase alpha | dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication | 0.581 |
ACACA | DHRS3 | ENSP00000344789 | ENSP00000365397 | acetyl-CoA carboxylase alpha | dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH | 0.581 |
ACACA | RDH10 | ENSP00000344789 | ENSP00000240285 | acetyl-CoA carboxylase alpha | retinol dehydrogenase 10 (all-trans); Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol | 0.581 |
ACACA | UBC | ENSP00000344789 | ENSP00000344818 | acetyl-CoA carboxylase alpha | ubiquitin C | 0.922 |
ACACB | ACACA | ENSP00000341044 | ENSP00000344789 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acetyl-CoA carboxylase alpha | 0.999 |
ACACB | DHRS1 | ENSP00000341044 | ENSP00000288111 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | dehydrogenase/reductase (SDR family) member 1 | 0.581 |
ACACB | DHRS2 | ENSP00000341044 | ENSP00000344674 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication | 0.581 |
ACACB | DHRS3 | ENSP00000341044 | ENSP00000365397 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | dehydrogenase/reductase (SDR family) member 3; Catalyzes the reduction of all-trans-retinal to all- trans-retinol in the presence of NADPH | 0.581 |
ACACB | RDH10 | ENSP00000341044 | ENSP00000240285 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | retinol dehydrogenase 10 (all-trans); Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol | 0.581 |
ACACB | UBC | ENSP00000341044 | ENSP00000344818 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | ubiquitin C | 0.851 |
DHRS1 | ACACA | ENSP00000288111 | ENSP00000344789 | dehydrogenase/reductase (SDR family) member 1 | acetyl-CoA carboxylase alpha | 0.581 |
DHRS1 | ACACB | ENSP00000288111 | ENSP00000341044 | dehydrogenase/reductase (SDR family) member 1 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.581 |
DHRS1 | DHRS2 | ENSP00000288111 | ENSP00000344674 | dehydrogenase/reductase (SDR family) member 1 | dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication | 0.625 |
DHRS1 | RDH10 | ENSP00000288111 | ENSP00000240285 | dehydrogenase/reductase (SDR family) member 1 | retinol dehydrogenase 10 (all-trans); Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol | 0.558 |
DHRS1 | SDPR | ENSP00000288111 | ENSP00000305675 | dehydrogenase/reductase (SDR family) member 1 | serum deprivation response; May play a role in targeting PRKCA to caveolae (By similarity) | 0.866 |
DHRS1 | UBC | ENSP00000288111 | ENSP00000344818 | dehydrogenase/reductase (SDR family) member 1 | ubiquitin C | 0.864 |
DHRS2 | ACACA | ENSP00000344674 | ENSP00000344789 | dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication | acetyl-CoA carboxylase alpha | 0.581 |
DHRS2 | ACACB | ENSP00000344674 | ENSP00000341044 | dehydrogenase/reductase (SDR family) member 2; Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2- propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.581 |