| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAD | CTPS1 | ENSP00000264705 | ENSP00000361699 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | 0.941 |
| CAD | CTPS2 | ENSP00000264705 | ENSP00000352222 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | CTP synthase 2; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides | 0.940 |
| CAD | DALRD3 | ENSP00000264705 | ENSP00000344989 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | DALR anticodon binding domain containing 3 | 0.824 |
| CAD | EPRS | ENSP00000264705 | ENSP00000355890 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | glutamyl-prolyl-tRNA synthetase | 0.972 |
| CAD | GMPS | ENSP00000264705 | ENSP00000419851 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division | 0.992 |
| CAD | PFAS | ENSP00000264705 | ENSP00000313490 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | phosphoribosylformylglycinamidine synthase | 0.987 |
| CAD | QARS | ENSP00000264705 | ENSP00000307567 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | glutaminyl-tRNA synthetase | 0.659 |
| CAD | THNSL1 | ENSP00000264705 | ENSP00000365534 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | threonine synthase-like 1 (S. cerevisiae) | 0.755 |
| CAD | UBC | ENSP00000264705 | ENSP00000344818 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | ubiquitin C | 0.874 |
| CAD | YARS | ENSP00000264705 | ENSP00000362576 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) | 0.733 |
| CTPS1 | CAD | ENSP00000361699 | ENSP00000264705 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.941 |
| CTPS1 | DALRD3 | ENSP00000361699 | ENSP00000344989 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | DALR anticodon binding domain containing 3 | 0.681 |
| CTPS1 | EPRS | ENSP00000361699 | ENSP00000355890 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | glutamyl-prolyl-tRNA synthetase | 0.704 |
| CTPS1 | GMPS | ENSP00000361699 | ENSP00000419851 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | guanine monphosphate synthetase; Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division | 0.973 |
| CTPS1 | PFAS | ENSP00000361699 | ENSP00000313490 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | phosphoribosylformylglycinamidine synthase | 0.796 |
| CTPS1 | QARS | ENSP00000361699 | ENSP00000307567 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | glutaminyl-tRNA synthetase | 0.510 |
| CTPS1 | UBC | ENSP00000361699 | ENSP00000344818 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | ubiquitin C | 0.986 |
| CTPS1 | YARS | ENSP00000361699 | ENSP00000362576 | CTP synthase 1; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) | 0.613 |
| CTPS2 | CAD | ENSP00000352222 | ENSP00000264705 | CTP synthase 2; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) | 0.940 |
| CTPS2 | DALRD3 | ENSP00000352222 | ENSP00000344989 | CTP synthase 2; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides | DALR anticodon binding domain containing 3 | 0.681 |
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