node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFEMP2 | FBLN1 | ENSP00000309953 | ENSP00000331544 | EGF containing fibulin-like extracellular matrix protein 2 | fibulin 1 | 0.911 |
EFEMP2 | FBLN5 | ENSP00000309953 | ENSP00000345008 | EGF containing fibulin-like extracellular matrix protein 2 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | 0.957 |
EFEMP2 | FBN1 | ENSP00000309953 | ENSP00000325527 | EGF containing fibulin-like extracellular matrix protein 2 | fibrillin 1; Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively | 0.641 |
EFEMP2 | LOX | ENSP00000309953 | ENSP00000231004 | EGF containing fibulin-like extracellular matrix protein 2 | lysyl oxidase; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression | 0.989 |
EFEMP2 | LOXL1 | ENSP00000309953 | ENSP00000261921 | EGF containing fibulin-like extracellular matrix protein 2 | lysyl oxidase-like 1; Active on elastin and collagen substrates (By similarity) | 0.418 |
EFEMP2 | MFAP2 | ENSP00000309953 | ENSP00000364685 | EGF containing fibulin-like extracellular matrix protein 2 | microfibrillar-associated protein 2; Component of the elastin-associated microfibrils | 0.936 |
EFEMP2 | MFAP4 | ENSP00000309953 | ENSP00000378957 | EGF containing fibulin-like extracellular matrix protein 2 | microfibrillar-associated protein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions | 0.905 |
EFEMP2 | MFAP5 | ENSP00000309953 | ENSP00000352455 | EGF containing fibulin-like extracellular matrix protein 2 | microfibrillar associated protein 5; Component of the elastin-associated microfibrils | 0.931 |
FBLN1 | EFEMP2 | ENSP00000331544 | ENSP00000309953 | fibulin 1 | EGF containing fibulin-like extracellular matrix protein 2 | 0.911 |
FBLN1 | FBLN5 | ENSP00000331544 | ENSP00000345008 | fibulin 1 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | 0.912 |
FBLN1 | MFAP2 | ENSP00000331544 | ENSP00000364685 | fibulin 1 | microfibrillar-associated protein 2; Component of the elastin-associated microfibrils | 0.935 |
FBLN1 | MFAP4 | ENSP00000331544 | ENSP00000378957 | fibulin 1 | microfibrillar-associated protein 4; Could be involved in calcium-dependent cell adhesion or intercellular interactions | 0.920 |
FBLN1 | MFAP5 | ENSP00000331544 | ENSP00000352455 | fibulin 1 | microfibrillar associated protein 5; Component of the elastin-associated microfibrils | 0.969 |
FBLN5 | EFEMP2 | ENSP00000345008 | ENSP00000309953 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | EGF containing fibulin-like extracellular matrix protein 2 | 0.957 |
FBLN5 | FBLN1 | ENSP00000345008 | ENSP00000331544 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | fibulin 1 | 0.912 |
FBLN5 | FBN1 | ENSP00000345008 | ENSP00000325527 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | fibrillin 1; Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1- containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively | 0.966 |
FBLN5 | FBN2 | ENSP00000345008 | ENSP00000262464 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | fibrillin 2; Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-2- containing microfibrils regulate the early process of elastic fiber assembly. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively (By similarity) | 0.912 |
FBLN5 | LOX | ENSP00000345008 | ENSP00000231004 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | lysyl oxidase; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression | 0.993 |
FBLN5 | LOXL1 | ENSP00000345008 | ENSP00000261921 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | lysyl oxidase-like 1; Active on elastin and collagen substrates (By similarity) | 0.998 |
FBLN5 | MFAP2 | ENSP00000345008 | ENSP00000364685 | fibulin 5; Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling | microfibrillar-associated protein 2; Component of the elastin-associated microfibrils | 0.943 |