CSRP1 protein (Homo sapiens) - STRING network view

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CSRP1

cysteine and glycine-rich protein 1; Could play a role in neuronal development (193 aa)

Predicted Functional Partners:

DVL2

0.808

LMO3

0.754

MED14

0.742

LMO1

0.682

ACTN1

0.680

UBC

0.630

CRP

0.576

LMO2

0.562

MACF1

0.557

GRB2

0.517

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN1	CSRP1	ENSP00000377941	ENSP00000345079	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	cysteine and glycine-rich protein 1; Could play a role in neuronal development	0.680
ACTN1	GRB2	ENSP00000377941	ENSP00000339007	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway	0.747
ACTN1	UBC	ENSP00000377941	ENSP00000344818	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	ubiquitin C	0.931
CRP	CSRP1	ENSP00000255030	ENSP00000345079	C-reactive protein, pentraxin-related; Displays several functions associated with host defense- it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells	cysteine and glycine-rich protein 1; Could play a role in neuronal development	0.576
CRP	GRB2	ENSP00000255030	ENSP00000339007	C-reactive protein, pentraxin-related; Displays several functions associated with host defense- it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway	0.517
CSRP1	ACTN1	ENSP00000345079	ENSP00000377941	cysteine and glycine-rich protein 1; Could play a role in neuronal development	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	0.680
CSRP1	CRP	ENSP00000345079	ENSP00000255030	cysteine and glycine-rich protein 1; Could play a role in neuronal development	C-reactive protein, pentraxin-related; Displays several functions associated with host defense- it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells	0.576
CSRP1	DVL2	ENSP00000345079	ENSP00000005340	cysteine and glycine-rich protein 1; Could play a role in neuronal development	dishevelled, dsh homolog 2 (Drosophila); Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity)	0.808
CSRP1	GRB2	ENSP00000345079	ENSP00000339007	cysteine and glycine-rich protein 1; Could play a role in neuronal development	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway	0.517
CSRP1	LMO1	ENSP00000345079	ENSP00000338207	cysteine and glycine-rich protein 1; Could play a role in neuronal development	LIM domain only 1 (rhombotin 1); May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors	0.682
CSRP1	LMO2	ENSP00000345079	ENSP00000257818	cysteine and glycine-rich protein 1; Could play a role in neuronal development	LIM domain only 2 (rhombotin-like 1); Acts with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state	0.562
CSRP1	LMO3	ENSP00000345079	ENSP00000312856	cysteine and glycine-rich protein 1; Could play a role in neuronal development	LIM domain only 3 (rhombotin-like 2)	0.754
CSRP1	MACF1	ENSP00000345079	ENSP00000354573	cysteine and glycine-rich protein 1; Could play a role in neuronal development	microtubule-actin crosslinking factor 1	0.557
CSRP1	MED14	ENSP00000345079	ENSP00000323720	cysteine and glycine-rich protein 1; Could play a role in neuronal development	mediator complex subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors	0.742
CSRP1	UBC	ENSP00000345079	ENSP00000344818	cysteine and glycine-rich protein 1; Could play a role in neuronal development	ubiquitin C	0.630
DVL2	CSRP1	ENSP00000005340	ENSP00000345079	dishevelled, dsh homolog 2 (Drosophila); Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity)	cysteine and glycine-rich protein 1; Could play a role in neuronal development	0.808
DVL2	UBC	ENSP00000005340	ENSP00000344818	dishevelled, dsh homolog 2 (Drosophila); Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity)	ubiquitin C	0.998
GRB2	ACTN1	ENSP00000339007	ENSP00000377941	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway	actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein	0.747
GRB2	CRP	ENSP00000339007	ENSP00000255030	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway	C-reactive protein, pentraxin-related; Displays several functions associated with host defense- it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells	0.517
GRB2	CSRP1	ENSP00000339007	ENSP00000345079	growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway	cysteine and glycine-rich protein 1; Could play a role in neuronal development	0.517

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