| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX25 | PIWIL1 | ENSP00000263576 | ENSP00000245255 | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | piwi-like 1 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and ot [...] | 0.585 |
| DDX25 | PIWIL2 | ENSP00000263576 | ENSP00000349208 | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | piwi-like 2 (Drosophila) | 0.511 |
| DDX25 | PIWIL4 | ENSP00000263576 | ENSP00000299001 | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | piwi-like 4 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated [...] | 0.512 |
| DDX25 | TDRD6 | ENSP00000263576 | ENSP00000346065 | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.645 |
| PIWIL1 | DDX25 | ENSP00000245255 | ENSP00000263576 | piwi-like 1 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and ot [...] | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | 0.585 |
| PIWIL1 | TDRD6 | ENSP00000245255 | ENSP00000346065 | piwi-like 1 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and ot [...] | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.936 |
| PIWIL2 | DDX25 | ENSP00000349208 | ENSP00000263576 | piwi-like 2 (Drosophila) | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | 0.511 |
| PIWIL2 | PIWIL4 | ENSP00000349208 | ENSP00000299001 | piwi-like 2 (Drosophila) | piwi-like 4 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated [...] | 0.411 |
| PIWIL2 | TDRD6 | ENSP00000349208 | ENSP00000346065 | piwi-like 2 (Drosophila) | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.573 |
| PIWIL4 | DDX25 | ENSP00000299001 | ENSP00000263576 | piwi-like 4 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated [...] | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | 0.512 |
| PIWIL4 | PIWIL2 | ENSP00000299001 | ENSP00000349208 | piwi-like 4 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated [...] | piwi-like 2 (Drosophila) | 0.411 |
| PIWIL4 | TDRD6 | ENSP00000299001 | ENSP00000346065 | piwi-like 4 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated [...] | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.690 |
| PTCRA | TDRD6 | ENSP00000304447 | ENSP00000346065 | pre T-cell antigen receptor alpha; The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development (By similarity) | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.746 |
| SLC25A41 | TDRD6 | ENSP00000322649 | ENSP00000346065 | solute carrier family 25, member 41 | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.634 |
| SNRPB | TDRD6 | ENSP00000412566 | ENSP00000346065 | small nuclear ribonucleoprotein polypeptides B and B1; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner (By similarity) | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.592 |
| SNRPN | TDRD6 | ENSP00000306223 | ENSP00000346065 | small nuclear ribonucleoprotein polypeptide N; May be involved in tissue-specific alternative RNA processing events | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.592 |
| SPATA19 | TDRD6 | ENSP00000299140 | ENSP00000346065 | spermatogenesis associated 19; May have a role in spermiogenesis | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.581 |
| TACC1 | TDRD6 | ENSP00000321703 | ENSP00000346065 | transforming, acidic coiled-coil containing protein 1 | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | 0.587 |
| TDRD6 | DDX25 | ENSP00000346065 | ENSP00000263576 | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | DEAD (Asp-Glu-Ala-Asp) box helicase 25; ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity) | 0.645 |
| TDRD6 | PIWIL1 | ENSP00000346065 | ENSP00000245255 | tudor domain containing 6; Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression (By similarity) | piwi-like 1 (Drosophila); Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and ot [...] | 0.936 |
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