Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | RPSA | ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. A [...] (295 aa) | ||||||||||||
Predicted Functional Partners:
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 | RPS21 | ribosomal protein S21 (83 aa) |
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0.999 | |||||||
 | RPS16 | ribosomal protein S16 (146 aa) |
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0.999 | ||||||
 | RPS5 | ribosomal protein S5 (204 aa) |
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0.999 | ||||||
 | RPS3A | ribosomal protein S3A; May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity) (264 aa) |
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0.999 | ||||||
 | RPS8 | ribosomal protein S8 (208 aa) |
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0.999 | |||||||
 | RPS3 | ribosomal protein S3 (243 aa) |
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0.999 | ||||||
 | RPS13 | ribosomal protein S13 (151 aa) |
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0.999 | ||||||
 | RPS14 | ribosomal protein S14 (151 aa) |
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0.999 | ||||||
 | FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (133 aa) |
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0.999 | |||||||
 | RPS20 | ribosomal protein S20 (142 aa) |
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0.999 | ||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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