| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GGT5 | GGT6 | ENSP00000381340 | ENSP00000458307 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | 0.770 |
| GGT5 | GPX4 | ENSP00000381340 | ENSP00000346103 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione peroxidase 4; Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity) | 0.944 |
| GGT5 | GSS | ENSP00000381340 | ENSP00000216951 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione synthetase | 0.903 |
| GGT5 | GSTA4 | ENSP00000381340 | ENSP00000359998 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione S-transferase alpha 4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE) | 0.901 |
| GGT5 | GSTM5 | ENSP00000381340 | ENSP00000256593 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione S-transferase mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles | 0.905 |
| GGT5 | GSTO1 | ENSP00000381340 | ENSP00000358727 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione S-transferase omega 1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid | 0.903 |
| GGT5 | GSTO2 | ENSP00000381340 | ENSP00000345023 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione S-transferase omega 2; Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) | 0.900 |
| GGT5 | GSTT1 | ENSP00000381340 | ENSP00000248935 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione S-transferase theta 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide | 0.907 |
| GGT5 | GSTT2B | ENSP00000381340 | ENSP00000290765 | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | glutathione S-transferase theta 2B (gene/pseudogene); Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity | 0.913 |
| GGT6 | GGT5 | ENSP00000458307 | ENSP00000381340 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | 0.770 |
| GGT6 | GPX4 | ENSP00000458307 | ENSP00000346103 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione peroxidase 4; Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity) | 0.923 |
| GGT6 | GSS | ENSP00000458307 | ENSP00000216951 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione synthetase | 0.909 |
| GGT6 | GSTA4 | ENSP00000458307 | ENSP00000359998 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione S-transferase alpha 4; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4- hydroxynonenal (4-HNE) | 0.900 |
| GGT6 | GSTM5 | ENSP00000458307 | ENSP00000256593 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione S-transferase mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles | 0.900 |
| GGT6 | GSTO1 | ENSP00000458307 | ENSP00000358727 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione S-transferase omega 1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid | 0.900 |
| GGT6 | GSTO2 | ENSP00000458307 | ENSP00000345023 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione S-transferase omega 2; Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) | 0.900 |
| GGT6 | GSTT1 | ENSP00000458307 | ENSP00000248935 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione S-transferase theta 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide | 0.906 |
| GGT6 | GSTT2B | ENSP00000458307 | ENSP00000290765 | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | glutathione S-transferase theta 2B (gene/pseudogene); Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity | 0.906 |
| GPX4 | GGT5 | ENSP00000346103 | ENSP00000381340 | glutathione peroxidase 4; Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity) | gamma-glutamyltransferase 5; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4) | 0.944 |
| GPX4 | GGT6 | ENSP00000346103 | ENSP00000458307 | glutathione peroxidase 4; Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity) | gamma-glutamyltransferase 6; Cleaves glutathione conjugates (By similarity) | 0.923 |
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