node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BPI | BPIFA1 | ENSP00000262865 | ENSP00000346251 | bactericidal/permeability-increasing protein | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | 0.569 |
BPIFA1 | BPI | ENSP00000346251 | ENSP00000262865 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | bactericidal/permeability-increasing protein | 0.569 |
BPIFA1 | BPIFB2 | ENSP00000346251 | ENSP00000170150 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | BPI fold containing family B, member 2 | 0.535 |
BPIFA1 | CDKN2B | ENSP00000346251 | ENSP00000276925 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest | 0.489 |
BPIFA1 | CETP | ENSP00000346251 | ENSP00000200676 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | 0.660 |
BPIFA1 | COX7B2 | ENSP00000346251 | ENSP00000305964 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | cytochrome c oxidase subunit VIIb2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | 0.811 |
BPIFA1 | MECOM | ENSP00000346251 | ENSP00000264674 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | MDS1 and EVI1 complex locus | 0.606 |
BPIFA1 | PLTP | ENSP00000346251 | ENSP00000361508 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | phospholipid transfer protein; Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that [...] | 0.748 |
BPIFA1 | SMAD6 | ENSP00000346251 | ENSP00000288840 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | SMAD family member 6; Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions | 0.556 |
BPIFA1 | TNFRSF19 | ENSP00000346251 | ENSP00000371693 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | tumor necrosis factor receptor superfamily, member 19; Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death | 0.563 |
BPIFA1 | WDR65 | ENSP00000346251 | ENSP00000435310 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | WD repeat domain 65 | 0.472 |
BPIFB2 | BPIFA1 | ENSP00000170150 | ENSP00000346251 | BPI fold containing family B, member 2 | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | 0.535 |
CDKN2B | BPIFA1 | ENSP00000276925 | ENSP00000346251 | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | 0.489 |
CDKN2B | COX7B2 | ENSP00000276925 | ENSP00000305964 | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest | cytochrome c oxidase subunit VIIb2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | 0.514 |
CETP | BPIFA1 | ENSP00000200676 | ENSP00000346251 | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | 0.660 |
COX7B2 | BPIFA1 | ENSP00000305964 | ENSP00000346251 | cytochrome c oxidase subunit VIIb2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | 0.811 |
COX7B2 | CDKN2B | ENSP00000305964 | ENSP00000276925 | cytochrome c oxidase subunit VIIb2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4); Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest | 0.514 |
COX7B2 | MECOM | ENSP00000305964 | ENSP00000264674 | cytochrome c oxidase subunit VIIb2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | MDS1 and EVI1 complex locus | 0.609 |
COX7B2 | TNFRSF19 | ENSP00000305964 | ENSP00000371693 | cytochrome c oxidase subunit VIIb2; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | tumor necrosis factor receptor superfamily, member 19; Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death | 0.606 |
MECOM | BPIFA1 | ENSP00000264674 | ENSP00000346251 | MDS1 and EVI1 complex locus | BPI fold containing family A, member 1; May be involved in the airway inflammatory response after exposure to irritants. May be associated with tumor progression. May play a role in innate immune responses of the upper airways | 0.606 |