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UBE2J2 UBE2J2 RABL2B RABL2B RABL2A RABL2A RAB11FIP4 RAB11FIP4 ACAP3 ACAP3 RAB25 RAB25 RAB11FIP3 RAB11FIP3 STX12 STX12 RAB11A RAB11A RAB11B RAB11B ARFGAP1 ARFGAP1
"ACAP3" - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene co-occurrence
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ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 3; GTPase-activating protein for the ADP ribosylation factor family (Potential) (834 aa)    
Predicted Functional Partners:
ARFGAP1
ADP-ribosylation factor GTPase activating protein 1 (414 aa)
        score_image   score_image score_image 0.708
UBE2J2
ubiquitin-conjugating enzyme E2, J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity) (275 aa)
            score_image   0.691
RABL2B
RAB, member of RAS oncogene family-like 2B (238 aa)
        score_image   score_image   0.633
RABL2A
RAB, member of RAS oncogene family-like 2A (228 aa)
        score_image   score_image   0.633
RAB25
RAB25, member RAS oncogene family; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Increases the rates of ovarian and breast cancers progression and aggressiveness by modulating cellular processes such as proliferation, survival and migration of epithelial tumor cells. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity) (213 aa)
        score_image   score_image   0.633
RAB11B
RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) (218 aa)
        score_image   score_image   0.633
RAB11A
RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] (216 aa)
        score_image   score_image   0.633
STX12
syntaxin 12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity) (276 aa)
        score_image       0.624
RAB11FIP4
RAB11 family interacting protein 4 (class II); Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an ’address tag’ delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6 (637 aa)
            score_image   0.593
RAB11FIP3
RAB11 family interacting protein 3 (class II) (756 aa)
            score_image   0.593
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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