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STRINGSTRING
SSRP1 SSRP1 ZFP91-CNTF ZFP91-CNTF FLG2 FLG2 ENSG00000258588 ENSG00000258588 SLC20A1 SLC20A1 TRAT1 TRAT1 BBOX1 BBOX1 BTBD2 BTBD2 BTBD1 BTBD1
"ENSG00000258588" - TRIM6-TRIM34 readthrough in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSG00000258588TRIM6-TRIM34 readthrough (842 aa)    
Predicted Functional Partners:
TRAT1
T cell receptor associated transmembrane adaptor 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells (186 aa)
             score_image   0.747
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; Catalyzes the formation of L-carnitine from gamma- butyrobetaine (387 aa)
             score_image   0.746
FLG2
filaggrin family member 2 (2391 aa)
             score_image   0.504
BTBD1
BTB (POZ) domain containing 1; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (482 aa)
             score_image   0.495
BTBD2
BTB (POZ) domain containing 2 (525 aa)
             score_image   0.495
SLC20A1
solute carrier family 20 (phosphate transporter), member 1; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus [...] (679 aa)
       score_image     score_image   0.421
ZFP91-CNTF
ZFP91-CNTF readthrough (non-protein coding) (529 aa)
             score_image   0.414
SSRP1
structure specific recognition protein 1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the ree [...] (709 aa)
         score_image   score_image   0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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