KCTD6 protein (Homo sapiens) - STRING network view

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KCTD6

potassium channel tetramerisation domain containing 6 (237 aa)

Predicted Functional Partners:

CUL3

0.821

USP11

0.740

OBSCN

0.729

UBC

0.698

OBSL1

0.614

ANK1

0.608

CTNND1

0.483

GSDMD

0.483

KCTD19

0.467

ZBTB49

0.463

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANK1	CUL3	ENSP00000265709	ENSP00000264414	ankyrin 1, erythrocytic	cullin 3; Core component of multiple cullin-RING-based BCR (BTB- CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR comple [...]	0.635
ANK1	KCTD6	ENSP00000265709	ENSP00000347188	ankyrin 1, erythrocytic	potassium channel tetramerisation domain containing 6	0.608
ANK1	OBSCN	ENSP00000265709	ENSP00000455507	ankyrin 1, erythrocytic	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.964
ANK1	UBC	ENSP00000265709	ENSP00000344818	ankyrin 1, erythrocytic	ubiquitin C	0.705
CTNND1	KCTD6	ENSP00000382004	ENSP00000347188	catenin (cadherin-associated protein), delta 1	potassium channel tetramerisation domain containing 6	0.483
CTNND1	UBC	ENSP00000382004	ENSP00000344818	catenin (cadherin-associated protein), delta 1	ubiquitin C	0.943
CUL3	ANK1	ENSP00000264414	ENSP00000265709	cullin 3; Core component of multiple cullin-RING-based BCR (BTB- CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR comple [...]	ankyrin 1, erythrocytic	0.635
CUL3	KCTD6	ENSP00000264414	ENSP00000347188	cullin 3; Core component of multiple cullin-RING-based BCR (BTB- CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR comple [...]	potassium channel tetramerisation domain containing 6	0.821
CUL3	UBC	ENSP00000264414	ENSP00000344818	cullin 3; Core component of multiple cullin-RING-based BCR (BTB- CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR comple [...]	ubiquitin C	0.999
GSDMD	KCTD6	ENSP00000262580	ENSP00000347188	gasdermin D	potassium channel tetramerisation domain containing 6	0.483
GSDMD	UBC	ENSP00000262580	ENSP00000344818	gasdermin D	ubiquitin C	0.795
KCTD19	KCTD6	ENSP00000305702	ENSP00000347188	potassium channel tetramerisation domain containing 19	potassium channel tetramerisation domain containing 6	0.467
KCTD6	ANK1	ENSP00000347188	ENSP00000265709	potassium channel tetramerisation domain containing 6	ankyrin 1, erythrocytic	0.608
KCTD6	CTNND1	ENSP00000347188	ENSP00000382004	potassium channel tetramerisation domain containing 6	catenin (cadherin-associated protein), delta 1	0.483
KCTD6	CUL3	ENSP00000347188	ENSP00000264414	potassium channel tetramerisation domain containing 6	cullin 3; Core component of multiple cullin-RING-based BCR (BTB- CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the BCR comple [...]	0.821
KCTD6	GSDMD	ENSP00000347188	ENSP00000262580	potassium channel tetramerisation domain containing 6	gasdermin D	0.483
KCTD6	KCTD19	ENSP00000347188	ENSP00000305702	potassium channel tetramerisation domain containing 6	potassium channel tetramerisation domain containing 19	0.467
KCTD6	OBSCN	ENSP00000347188	ENSP00000455507	potassium channel tetramerisation domain containing 6	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.729
KCTD6	OBSL1	ENSP00000347188	ENSP00000385636	potassium channel tetramerisation domain containing 6	obscurin-like 1; Regulates CUL7-FBXW8-containing ubiquitin ligase complex, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Localizes CUL7 to the Golgi apparatus in neurons	0.614
KCTD6	UBC	ENSP00000347188	ENSP00000344818	potassium channel tetramerisation domain containing 6	ubiquitin C	0.698

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