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ADPRM ADPRM PPAPDC1B PPAPDC1B UAP1L1 UAP1L1 WDR81 WDR81 AGK AGK PPAPDC1A PPAPDC1A UAP1 UAP1 NYX NYX PAPL PAPL ACP5 ACP5 GUCY2C GUCY2C
"AGK" - acylglycerol kinase in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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AGKacylglycerol kinase; Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth (422 aa)    
Predicted Functional Partners:
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1; Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P (505 aa)
            score_image   0.714
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 (507 aa)
            score_image   0.583
WDR81
WD repeat domain 81 (1941 aa)
            score_image   0.552
NYX
nyctalopin (481 aa)
            score_image   0.534
ADPRM
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent; Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP- choline and CDP-ethanolamine, but not other non-reducing ADP- sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity) (342 aa)
score_image               0.461
PAPL
Iron/zinc purple acid phosphatase-like protein (438 aa)
score_image               0.461
ACP5
acid phosphatase 5, tartrate resistant; Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias (325 aa)
score_image               0.461
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor); Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin (1073 aa)
            score_image   0.433
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma (264 aa)
score_image       score_image   score_image   0.409
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A; Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol (271 aa)
score_image       score_image   score_image   0.409
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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