| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COPS7A | DNAJC19 | ENSP00000229251 | ENSP00000372005 | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | 0.552 |
| COPS7A | MARVELD1 | ENSP00000229251 | ENSP00000441365 | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | MARVEL domain containing 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity) | 0.576 |
| COPS7A | MRPL39 | ENSP00000229251 | ENSP00000305682 | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | mitochondrial ribosomal protein L39 | 0.474 |
| COPS7A | TPRA1 | ENSP00000229251 | ENSP00000347748 | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | transmembrane protein, adipocyte asscociated 1 | 0.541 |
| COPS7A | UBC | ENSP00000229251 | ENSP00000344818 | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | ubiquitin C | 0.734 |
| DNAJC19 | COPS7A | ENSP00000372005 | ENSP00000229251 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | 0.552 |
| DNAJC19 | GTP | ENSP00000372005 | ENSP00000323047 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | Mitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) | 0.508 |
| DNAJC19 | MARVELD1 | ENSP00000372005 | ENSP00000441365 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | MARVEL domain containing 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity) | 0.634 |
| DNAJC19 | MRPL39 | ENSP00000372005 | ENSP00000305682 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | mitochondrial ribosomal protein L39 | 0.555 |
| DNAJC19 | MTG1 | ENSP00000372005 | ENSP00000436767 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | mitochondrial GTPase 1 homolog (S. cerevisiae); Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) | 0.489 |
| DNAJC19 | TPRA1 | ENSP00000372005 | ENSP00000347748 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | transmembrane protein, adipocyte asscociated 1 | 0.617 |
| DNAJC19 | UBC | ENSP00000372005 | ENSP00000344818 | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | ubiquitin C | 0.512 |
| GPR149 | TPRA1 | ENSP00000374390 | ENSP00000347748 | G protein-coupled receptor 149; Orphan receptor | transmembrane protein, adipocyte asscociated 1 | 0.484 |
| GTP | DNAJC19 | ENSP00000323047 | ENSP00000372005 | Mitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | 0.508 |
| GTP | MARVELD1 | ENSP00000323047 | ENSP00000441365 | Mitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) | MARVEL domain containing 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity) | 0.546 |
| GTP | MRPL39 | ENSP00000323047 | ENSP00000305682 | Mitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) | mitochondrial ribosomal protein L39 | 0.658 |
| GTP | TPRA1 | ENSP00000323047 | ENSP00000347748 | Mitochondrial GTPase 1 ; Mitochondrial GTPase. May be involved in assembly of the large ribosomal subunit (By similarity) | transmembrane protein, adipocyte asscociated 1 | 0.477 |
| HLA-DMA | TPRA1 | ENSP00000363976 | ENSP00000347748 | major histocompatibility complex, class II, DM alpha | transmembrane protein, adipocyte asscociated 1 | 0.584 |
| MARVELD1 | COPS7A | ENSP00000441365 | ENSP00000229251 | MARVEL domain containing 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity) | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis); Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association w [...] | 0.576 |
| MARVELD1 | DNAJC19 | ENSP00000441365 | ENSP00000372005 | MARVEL domain containing 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration (By similarity) | DnaJ (Hsp40) homolog, subfamily C, member 19; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity) | 0.634 |
Share
