| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BANK1 | BLK | ENSP00000320509 | ENSP00000259089 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | 0.765 |
| BANK1 | FAM167A | ENSP00000320509 | ENSP00000284486 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | family with sequence similarity 167, member A | 0.725 |
| BANK1 | PHRF1 | ENSP00000320509 | ENSP00000410626 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | PHD and ring finger domains 1 | 0.700 |
| BANK1 | PXK | ENSP00000320509 | ENSP00000348472 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | PX domain containing serine/threonine kinase | 0.658 |
| BANK1 | UHRF1BP1 | ENSP00000320509 | ENSP00000192788 | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | UHRF1 binding protein 1; May act as a negative regulator of cell growth | 0.508 |
| BLK | BANK1 | ENSP00000259089 | ENSP00000320509 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | 0.765 |
| BLK | EGFR | ENSP00000259089 | ENSP00000275493 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | epidermal growth factor receptor | 0.958 |
| BLK | FAM167A | ENSP00000259089 | ENSP00000284486 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | family with sequence similarity 167, member A | 0.873 |
| BLK | ITGAM | ENSP00000259089 | ENSP00000441691 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | integrin, alpha M (complement component 3 receptor 3 subunit); Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain | 0.509 |
| BLK | PHRF1 | ENSP00000259089 | ENSP00000410626 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | PHD and ring finger domains 1 | 0.723 |
| BLK | PXK | ENSP00000259089 | ENSP00000348472 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | PX domain containing serine/threonine kinase | 0.742 |
| BLK | UHRF1BP1 | ENSP00000259089 | ENSP00000192788 | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | UHRF1 binding protein 1; May act as a negative regulator of cell growth | 0.726 |
| EGFR | BLK | ENSP00000275493 | ENSP00000259089 | epidermal growth factor receptor | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | 0.958 |
| EGFR | PIK3R1 | ENSP00000275493 | ENSP00000274335 | epidermal growth factor receptor | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.999 |
| EGFR | PXK | ENSP00000275493 | ENSP00000348472 | epidermal growth factor receptor | PX domain containing serine/threonine kinase | 0.809 |
| FAM167A | BANK1 | ENSP00000284486 | ENSP00000320509 | family with sequence similarity 167, member A | B-cell scaffold protein with ankyrin repeats 1; Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2 | 0.725 |
| FAM167A | BLK | ENSP00000284486 | ENSP00000259089 | family with sequence similarity 167, member A | B lymphoid tyrosine kinase; Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis do [...] | 0.873 |
| FAM167A | ITGAM | ENSP00000284486 | ENSP00000441691 | family with sequence similarity 167, member A | integrin, alpha M (complement component 3 receptor 3 subunit); Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain | 0.584 |
| FAM167A | PHRF1 | ENSP00000284486 | ENSP00000410626 | family with sequence similarity 167, member A | PHD and ring finger domains 1 | 0.814 |
| FAM167A | PXK | ENSP00000284486 | ENSP00000348472 | family with sequence similarity 167, member A | PX domain containing serine/threonine kinase | 0.823 |
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