node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARID4A | RBBP6 | ENSP00000347602 | ENSP00000317872 | AT rich interactive domain 4A (RBP1-like); Interacts with the viral protein-binding domain of the retinoblastoma protein | retinoblastoma binding protein 6 | 0.754 |
ARID4A | SON | ENSP00000347602 | ENSP00000348984 | AT rich interactive domain 4A (RBP1-like); Interacts with the viral protein-binding domain of the retinoblastoma protein | SON DNA binding protein | 0.681 |
DIDO1 | SON | ENSP00000266070 | ENSP00000348984 | death inducer-obliterator 1 | SON DNA binding protein | 0.662 |
DIDO1 | U2AF1 | ENSP00000266070 | ENSP00000291552 | death inducer-obliterator 1 | U2 small nuclear RNA auxiliary factor 1; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3’-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron | 0.644 |
DIDO1 | UBC | ENSP00000266070 | ENSP00000344818 | death inducer-obliterator 1 | ubiquitin C | 0.622 |
ILF3 | MAGOH | ENSP00000404121 | ENSP00000360525 | interleukin enhancer binding factor 3, 90kDa | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | 0.996 |
ILF3 | SON | ENSP00000404121 | ENSP00000348984 | interleukin enhancer binding factor 3, 90kDa | SON DNA binding protein | 0.671 |
ILF3 | UBC | ENSP00000404121 | ENSP00000344818 | interleukin enhancer binding factor 3, 90kDa | ubiquitin C | 0.969 |
MAGOH | ILF3 | ENSP00000360525 | ENSP00000404121 | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | interleukin enhancer binding factor 3, 90kDa | 0.996 |
MAGOH | SON | ENSP00000360525 | ENSP00000348984 | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | SON DNA binding protein | 0.996 |
MAGOH | SRSF5 | ENSP00000360525 | ENSP00000377892 | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | serine/arginine-rich splicing factor 5; Plays a role in constitutive splicing and can modulate the selection of alternative splice sites | 0.999 |
MAGOH | SRSF7 | ENSP00000360525 | ENSP00000325905 | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | serine/arginine-rich splicing factor 7; Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10 | 0.999 |
MAGOH | U2AF1 | ENSP00000360525 | ENSP00000291552 | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | U2 small nuclear RNA auxiliary factor 1; Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3’-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron | 0.936 |
MAGOH | UBC | ENSP00000360525 | ENSP00000344818 | mago-nashi homolog, proliferation-associated (Drosophila); Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mR [...] | ubiquitin C | 0.927 |
RBBP6 | ARID4A | ENSP00000317872 | ENSP00000347602 | retinoblastoma binding protein 6 | AT rich interactive domain 4A (RBP1-like); Interacts with the viral protein-binding domain of the retinoblastoma protein | 0.754 |
RBBP6 | SON | ENSP00000317872 | ENSP00000348984 | retinoblastoma binding protein 6 | SON DNA binding protein | 0.818 |
RBBP6 | UBC | ENSP00000317872 | ENSP00000344818 | retinoblastoma binding protein 6 | ubiquitin C | 0.731 |
SON | ARID4A | ENSP00000348984 | ENSP00000347602 | SON DNA binding protein | AT rich interactive domain 4A (RBP1-like); Interacts with the viral protein-binding domain of the retinoblastoma protein | 0.681 |
SON | DIDO1 | ENSP00000348984 | ENSP00000266070 | SON DNA binding protein | death inducer-obliterator 1 | 0.662 |
SON | ILF3 | ENSP00000348984 | ENSP00000404121 | SON DNA binding protein | interleukin enhancer binding factor 3, 90kDa | 0.671 |