MYO16 protein (Homo sapiens) - STRING network view

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MYO16

myosin XVI (1858 aa)

Predicted Functional Partners:

PPP1CC

0.576

PPP1CA

0.576

ACOT9

0.570

NCKAP1

0.570

CYFIP1

0.570

ARHGAP26

0.570

PIK3R1

0.570

XRRA1

0.531

BTNL3

0.504

MYO15B

0.501

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOT9	MYO16	ENSP00000368605	ENSP00000349145	acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs	myosin XVI	0.570
ARHGAP26	MYO16	ENSP00000274498	ENSP00000349145	Rho GTPase activating protein 26; GTPase-activating protein for RHOA and CDC42	myosin XVI	0.570
BTNL3	MYO16	ENSP00000341787	ENSP00000349145	butyrophilin-like 3	myosin XVI	0.504
CYFIP1	MYO16	ENSP00000324549	ENSP00000349145	cytoplasmic FMR1 interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the [...]	myosin XVI	0.570
CYFIP1	NCKAP1	ENSP00000324549	ENSP00000354251	cytoplasmic FMR1 interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the [...]	NCK-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1	0.999
MYO15B	MYO16	ENSP00000293201	ENSP00000349145	myosin XVB pseudogene	myosin XVI	0.501
MYO16	ACOT9	ENSP00000349145	ENSP00000368605	myosin XVI	acyl-CoA thioesterase 9; Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active on long chain acyl-CoAs	0.570
MYO16	ARHGAP26	ENSP00000349145	ENSP00000274498	myosin XVI	Rho GTPase activating protein 26; GTPase-activating protein for RHOA and CDC42	0.570
MYO16	BTNL3	ENSP00000349145	ENSP00000341787	myosin XVI	butyrophilin-like 3	0.504
MYO16	CYFIP1	ENSP00000349145	ENSP00000324549	myosin XVI	cytoplasmic FMR1 interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the [...]	0.570
MYO16	MYO15B	ENSP00000349145	ENSP00000293201	myosin XVI	myosin XVB pseudogene	0.501
MYO16	NCKAP1	ENSP00000349145	ENSP00000354251	myosin XVI	NCK-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1	0.570
MYO16	PIK3R1	ENSP00000349145	ENSP00000274335	myosin XVI	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.570
MYO16	PPP1CA	ENSP00000349145	ENSP00000326031	myosin XVI	protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent p [...]	0.576
MYO16	PPP1CC	ENSP00000349145	ENSP00000335084	myosin XVI	protein phosphatase 1, catalytic subunit, gamma isozyme; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- associated Ca [...]	0.576
MYO16	XRRA1	ENSP00000349145	ENSP00000339918	myosin XVI	X-ray radiation resistance associated 1; May be involved in the response of cells to X-ray radiation	0.531
NCKAP1	CYFIP1	ENSP00000354251	ENSP00000324549	NCK-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1	cytoplasmic FMR1 interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the [...]	0.999
NCKAP1	MYO16	ENSP00000354251	ENSP00000349145	NCK-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1	myosin XVI	0.570
PIK3R1	MYO16	ENSP00000274335	ENSP00000349145	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	myosin XVI	0.570
PPP1CA	MYO16	ENSP00000326031	ENSP00000349145	protein phosphatase 1, catalytic subunit, alpha isozyme; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent p [...]	myosin XVI	0.576

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