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FNDC3A FNDC3A HPSE2 HPSE2 CRABP2 CRABP2 COX11 COX11 CNNM1 CNNM1 YBEY YBEY TUSC3 TUSC3 MRS2 MRS2 MAGT1 MAGT1 TRPM6 TRPM6 NIPA1 NIPA1
"CNNM1" - cyclin M1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
CNNM1cyclin M1; Probable metal transporter (By similarity) (951 aa)    
Predicted Functional Partners:
HPSE2
heparanase 2; Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro) (592 aa)
            score_image   0.889
CRABP2
cellular retinoic acid binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors (138 aa)
            score_image   0.860
FNDC3A
fibronectin type III domain containing 3A (1198 aa)
            score_image   0.759
COX11
cytochrome c oxidase assembly homolog 11 (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) (276 aa)
            score_image   0.616
MAGT1
magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells (367 aa)
            score_image   0.581
MRS2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae); Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix (443 aa)
            score_image   0.559
YBEY
ybeY metallopeptidase (putative) (167 aa)
score_image           score_image   0.552
TUSC3
tumor suppressor candidate 3; Magnesium transporter. May be involved in N- glycosylation through its association with N-oligosaccharyl transferase (348 aa)
            score_image   0.522
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) (329 aa)
            score_image   0.491
TRPM6
transient receptor potential cation channel, subfamily M, member 6; Essential ion channel and serine/threonine-protein kinase. Crucial for magnesium homeostasis. Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. Isoforms of the type M6-kinase lack the ion channel region (2022 aa)
            score_image   0.485
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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