Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
MIS12 MIS12 C12orf50 C12orf50 POC1B POC1B C12orf29 C12orf29 RASSF9 RASSF9 SFT2D1 SFT2D1 UBC UBC CEP290 CEP290
"C12orf29" - chromosome 12 open reading frame 29 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf29chromosome 12 open reading frame 29 (325 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.774
POC1B
POC1 centriolar protein homolog B (Chlamydomonas); Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis (478 aa)
            score_image   0.660
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; May play a role in regulating vesicuar trafficking in cells (By similarity) (435 aa)
            score_image   0.659
C12orf50
chromosome 12 open reading frame 50 (414 aa)
            score_image   0.591
SFT2D1
SFT2 domain containing 1; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (159 aa)
            score_image   0.508
CEP290
centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes (2479 aa)
            score_image   0.430
MIS12
MIS12, MIND kinetochore complex component, homolog (S. pombe); Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (205 aa)
            score_image   0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (41%)