| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC141 | MYBPHL | ENSP00000395995 | ENSP00000349678 | coiled-coil domain containing 141 | myosin binding protein H-like | 0.407 |
| CELSR2 | MLXIPL | ENSP00000271332 | ENSP00000320886 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | MLX interacting protein-like | 0.562 |
| CELSR2 | MYBPHL | ENSP00000271332 | ENSP00000349678 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | myosin binding protein H-like | 0.537 |
| CELSR2 | PSRC1 | ENSP00000271332 | ENSP00000358919 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | proline/serine-rich coiled-coil 1; Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression | 0.813 |
| CELSR2 | SORT1 | ENSP00000271332 | ENSP00000256637 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] | 0.757 |
| EME2 | MYBPHL | ENSP00000303779 | ENSP00000349678 | essential meiotic endonuclease 1 homolog 2 (S. pombe); Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3’-flap structures | myosin binding protein H-like | 0.459 |
| MLXIPL | CELSR2 | ENSP00000320886 | ENSP00000271332 | MLX interacting protein-like | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | 0.562 |
| MLXIPL | MYBPHL | ENSP00000320886 | ENSP00000349678 | MLX interacting protein-like | myosin binding protein H-like | 0.406 |
| MLXIPL | PSRC1 | ENSP00000320886 | ENSP00000358919 | MLX interacting protein-like | proline/serine-rich coiled-coil 1; Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression | 0.512 |
| MLXIPL | SORT1 | ENSP00000320886 | ENSP00000256637 | MLX interacting protein-like | sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] | 0.580 |
| MYBPHL | CCDC141 | ENSP00000349678 | ENSP00000395995 | myosin binding protein H-like | coiled-coil domain containing 141 | 0.407 |
| MYBPHL | CELSR2 | ENSP00000349678 | ENSP00000271332 | myosin binding protein H-like | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | 0.537 |
| MYBPHL | EME2 | ENSP00000349678 | ENSP00000303779 | myosin binding protein H-like | essential meiotic endonuclease 1 homolog 2 (S. pombe); Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3’-flap structures | 0.459 |
| MYBPHL | MLXIPL | ENSP00000349678 | ENSP00000320886 | myosin binding protein H-like | MLX interacting protein-like | 0.406 |
| MYBPHL | PSRC1 | ENSP00000349678 | ENSP00000358919 | myosin binding protein H-like | proline/serine-rich coiled-coil 1; Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression | 0.514 |
| MYBPHL | RRP1 | ENSP00000349678 | ENSP00000417464 | myosin binding protein H-like | ribosomal RNA processing 1 homolog (S. cerevisiae); Plays a critical role in the generation of 28S rRNA | 0.517 |
| MYBPHL | RRP1B | ENSP00000349678 | ENSP00000339145 | myosin binding protein H-like | ribosomal RNA processing 1 homolog B (S. cerevisiae) | 0.517 |
| MYBPHL | SORT1 | ENSP00000349678 | ENSP00000256637 | myosin binding protein H-like | sortilin 1; Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic diff [...] | 0.504 |
| MYBPHL | SPINT1 | ENSP00000349678 | ENSP00000342098 | myosin binding protein H-like | serine peptidase inhibitor, Kunitz type 1; Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14) | 0.446 |
| PSRC1 | CELSR2 | ENSP00000358919 | ENSP00000271332 | proline/serine-rich coiled-coil 1; Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); Receptor that may have an important role in cell/cell signaling during nervous system formation | 0.813 |
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