Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | ZMYM6 | zinc finger, MYM-type 6 (1325 aa) | ||||||||||||
Predicted Functional Partners:
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 | ZNF280B | zinc finger protein 280B; May function as a transcription factor (543 aa) |
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0.806 | |||||||||
 | POGZ | pogo transposable element with ZNF domain (1410 aa) |
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0.806 | |||||||||
 | ZNF280C | zinc finger protein 280C; May function as a transcription factor (737 aa) |
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0.805 | |||||||||
 | ZNF280A | zinc finger protein 280A; May function as a transcription factor (542 aa) |
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0.805 | |||||||||
 | ZNF280D | zinc finger protein 280D; May function as a transcription factor (979 aa) |
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0.805 | |||||||||
 | KLHL13 | kelch-like 13 (Drosophila) (658 aa) |
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0.740 | ||||||||||
 | C10orf11 | chromosome 10 open reading frame 11 (198 aa) |
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0.607 | ||||||||||
 | CDK9 | cyclin-dependent kinase 9; Protein kinase involved in the regulation of transcription. Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A, SUPT5H and RDBP. This complex is inactive when in the 7SK snRNP complex form. Phosphorylates EP300, MYOD1, RPB1/POLR2A and AR, and the negative elongation factors DSIF and NELF. Regulates cytok [...] (372 aa) |
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0.603 | |||||||||
 | CPXM1 | carboxypeptidase X (M14 family), member 1; May be involved in cell-cell interactions. No carboxypeptidase activity was found yet (By similarity) (734 aa) |
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0.531 | ||||||||||
 | SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix (318 aa) |
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0.499 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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