node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LAGE3 | OSGEP | ENSP00000349923 | ENSP00000206542 | L antigen family, member 3 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) | 0.750 |
LAGE3 | PUM1 | ENSP00000349923 | ENSP00000391723 | L antigen family, member 3 | pumilio homolog 1 (Drosophila); Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3’-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity) | 0.644 |
LAGE3 | RAB5B | ENSP00000349923 | ENSP00000353444 | L antigen family, member 3 | RAB5B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | 0.644 |
LAGE3 | SEPHS2 | ENSP00000349923 | ENSP00000426234 | L antigen family, member 3 | selenophosphate synthetase 2; Synthesizes selenophosphate from selenide and ATP | 0.644 |
LAGE3 | TOM1L2 | ENSP00000349923 | ENSP00000368818 | L antigen family, member 3 | target of myb1-like 2 (chicken); Probable role in protein transport. May regulate growth factor-induced mitogenic signaling | 0.644 |
LAGE3 | TP53RK | ENSP00000349923 | ENSP00000361186 | L antigen family, member 3 | TP53 regulating kinase; Protein kinase that phosphorylates ’Ser-15’ of p53/TP53 protein and may therefore participate in its activation | 0.905 |
LAGE3 | UBC | ENSP00000349923 | ENSP00000344818 | L antigen family, member 3 | ubiquitin C | 0.925 |
LAGE3 | UBL4A | ENSP00000349923 | ENSP00000358674 | L antigen family, member 3 | ubiquitin-like 4A; Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40- it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting | 0.814 |
LAGE3 | USP34 | ENSP00000349923 | ENSP00000381577 | L antigen family, member 3 | ubiquitin specific peptidase 34 | 0.646 |
LAGE3 | ZFYVE19 | ENSP00000349923 | ENSP00000347498 | L antigen family, member 3 | zinc finger, FYVE domain containing 19 | 0.644 |
OSGEP | LAGE3 | ENSP00000206542 | ENSP00000349923 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) | L antigen family, member 3 | 0.750 |
OSGEP | TP53RK | ENSP00000206542 | ENSP00000361186 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) | TP53 regulating kinase; Protein kinase that phosphorylates ’Ser-15’ of p53/TP53 protein and may therefore participate in its activation | 0.999 |
OSGEP | UBC | ENSP00000206542 | ENSP00000344818 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) | ubiquitin C | 0.483 |
PUM1 | LAGE3 | ENSP00000391723 | ENSP00000349923 | pumilio homolog 1 (Drosophila); Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3’-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity) | L antigen family, member 3 | 0.644 |
PUM1 | UBC | ENSP00000391723 | ENSP00000344818 | pumilio homolog 1 (Drosophila); Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3’-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity) | ubiquitin C | 0.938 |
RAB5B | LAGE3 | ENSP00000353444 | ENSP00000349923 | RAB5B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | L antigen family, member 3 | 0.644 |
RAB5B | UBC | ENSP00000353444 | ENSP00000344818 | RAB5B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | ubiquitin C | 0.659 |
RAB5B | ZFYVE19 | ENSP00000353444 | ENSP00000347498 | RAB5B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | zinc finger, FYVE domain containing 19 | 0.415 |
SEPHS2 | LAGE3 | ENSP00000426234 | ENSP00000349923 | selenophosphate synthetase 2; Synthesizes selenophosphate from selenide and ATP | L antigen family, member 3 | 0.644 |
SEPHS2 | UBC | ENSP00000426234 | ENSP00000344818 | selenophosphate synthetase 2; Synthesizes selenophosphate from selenide and ATP | ubiquitin C | 0.492 |